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  1. The Black Swan Theory was described by Nassim Nicholas Taleb in his book “The Black Swan”. This theory refers to “high-impact, hard-to-predict, and rare events beyond the realm of normal expectations”. Accordi...

    Authors: Marco Vacante, Velia D’Agata, Massimo Motta, Giulia Malaguarnera, Antonio Biondi, Francesco Basile, Michele Malaguarnera, Caterina Gagliano, Filippo Drago and Salvatore Salamone

    Citation: BMC Surgery 2012 12(Suppl 1):S36

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  2. Colorectal cancer represents the most common malignancy of the gastrointestinal tract. Owing to differences in dietary habits and lifestyle, this neoplasm is more common in industrialized countries than in dev...

    Authors: Mario Uccello, Giulia Malaguarnera, Francesco Basile, Velia D’agata, Michele Malaguarnera, Gaetano Bertino, Marco Vacante, Filippo Drago and Antonio Biondi

    Citation: BMC Surgery 2012 12(Suppl 1):S35

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  3. The case presented by the authors gives the opportunity to discuss the medico-legal issues related to lack of prevention of falls in elderly hospitalized patients.

    Authors: Claudio Terranova, Fabrizio Cardin, Bruno Martella, Bruno Amato and Carmelo Militello

    Citation: BMC Surgery 2012 12(Suppl 1):S34

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  4. We studied the possible correlation between age, testosterone deficiency, cavernosal fibrosis and erectile dysfunction (ED).

    Authors: Fabrizio Iacono, Domenico Prezioso, Antonio Ruffo, Ester Illiano, Leo Romis, G Di Lauro, Giuseppe Romeo and Bruno Amato

    Citation: BMC Surgery 2012 12(Suppl 1):S24

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  5. Reduced libido is widely considered the most prominent symptomatic reflection of low testosterone (T) levels in men. Testosterone deficiency (TD) afflicts approximately 30% of men aged 40-79 years. This study ...

    Authors: Fabrizio Iacono, Domenico Prezioso, Ester Illiano, Giuseppe Romeo, Antonio Ruffo and Bruno Amato

    Citation: BMC Surgery 2012 12(Suppl 1):S23

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  6. Anastomotic leakage is a major complication in colorectal surgery and with an incidence of 11% the most common cause of morbidity and mortality. In order to reduce the incidence of anastomotic leakage the C-se...

    Authors: Ilsalien S Bakker, Annelien N Morks, Henk O ten Cate Hoedemaker, Johannes G M Burgerhof, Henri G Leuvenink, Rutger J Ploeg and Klaas Havenga

    Citation: BMC Surgery 2012 12:23

    Content type: Study protocol

    Published on:

  7. Lower urinary tract symptoms (LUTS) are associated with great emotional costs to individuals and substantial economic costs to society. This study seeks to evaluate the effe...

    Authors: Fabrizio Iacono, Domenico Prezioso, Ester Illiano, Antonio Ruffo, Giuseppe Romeo and Bruno Amato

    Citation: BMC Surgery 2012 12(Suppl 1):S22

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

    The Retraction Note to this article has been published in BMC Surgery 2016 16:23

  8. Increased life expectancy has led to elevating the mean age of the patients at the time of diagnosis of colon cancer and subsequent treatment. Differences in complication rates and outcome between elderly and ...

    Authors: Giuseppe Grosso, Antonio Biondi, Stefano Marventano, Antonio Mistretta, Giorgio Calabrese and Francesco Basile

    Citation: BMC Surgery 2012 12(Suppl 1):S20

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  9. The incidence of lower extremity peripheral artery disease (LE-PAD) continues to increase and associated morbidity remains high. Despite the significant development of percutaneous revascularization strategies...

    Authors: Anna Franzone, Marco Ferrone, Giuseppe Carotenuto, Andreina Carbone, Laura Scudiero, Federica Serino, Fernando Scudiero, Raffaele Izzo, Raffaele Piccolo, Savio Saviano, Bruno Amato, Cinzia Perrino, Bruno Trimarco and Giovanni Esposito

    Citation: BMC Surgery 2012 12(Suppl 1):S13

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  10. The inguinal hernia is one of the most common diseases in the elderly. Treatment of this type of pathology is exclusively surgical and relies almost always on the use of local anesthesia. While in the past her...

    Authors: Rita Compagna, Gabriele Vigliotti, Guido Coretti, Maurizio Amato, Giovanni Aprea, Alessandro Puzziello, Carmelo Militello, Fabrizio Iacono, Domenico Prezioso and Bruno Amato

    Citation: BMC Surgery 2012 12(Suppl 1):S12

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  11. To determine whether patients with no alarm signs who ask the endoscopist to shorten their waiting time due to test result anxiety, represent a risk category for a major organic pathology.

    Authors: Fabrizio Cardin, Alessandra Andreotti, Manuel Zorzi, Claudio Terranova, Bruno Martella, Bruno Amato and Carmelo Militello

    Citation: BMC Surgery 2012 12(Suppl 1):S11

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  12. Differences in health-related quality of life perception in patients with chronic disease may depend on pre-existing differences in personality profile. The purpose of the study was to investigate in a cohort ...

    Authors: Fabrizio Cardin, Francesco Ambrosio, Piero Amodio, Lina Minazzato, Giancarlo Bombonato, Sami Schiff, Katiuscia Finotti, Daria Giuliani, Tonino Bianco, Claudio Terranova, Carmelo Militello and Carlo Ori

    Citation: BMC Surgery 2012 12(Suppl 1):S10

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  13. To study the relationship between endoscopic practice and adverse events during colonoscopy under standard deep sedation induced and monitored by an anesthetist.

    Authors: Fabrizio Cardin, Nadia Minicuci, Federico Campigotto, Alessandra Andreotti, Elisa Granziaera, Barbara Donà, Bruno Martella, Claudio Terranova and Carmelo Militello

    Citation: BMC Surgery 2012 12(Suppl 1):S9

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  14. The aim of this study was to define any benefits in terms of early outcome for laparoscopic colectomy in patients over 75 years old (OP) compared with the outcomes of a younger populations (YP).

    Authors: Vincenzo Bottino, Maria Grazia Esposito, Arianna Mottola, Giampaolo Marte, Vittorio Di Maio, Valerio Sciascia, Marco Nunziante, Giovanni Fregola, Salvatore Cuzzovaglia, Francesco Galante, Federica Andreoli, Alfredo Breglia, Maria Elena Giuliano, Domenico Papaleo, Paola Della Rocca and Pietro Maida

    Citation: BMC Surgery 2012 12(Suppl 1):S8

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  15. Cholecystectomy, gold standard treatment for gallbladder lithiasis, is closely associated with increased bile reflux into the stomach as amply demonstrated by experimental studies. The high prevalence of galls...

    Authors: Giovanni Aprea, Alfonso Canfora, Antonio Ferronetti, Antonio Giugliano, Francesco Guida, Antonio Braun, Melania Battaglini Ciciriello, Federica Tovecci, Giovanni Mastrobuoni, Fabrizio Cardin and Bruno Amato

    Citation: BMC Surgery 2012 12(Suppl 1):S5

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  16. The gastro-esophageal reflux disease (GERD) is one of the most frequent disease of the upper gastro-entheric tract. Surgical treatment is reserved to selected patients, affected by severe forms of disease and/...

    Authors: Giovanni Aprea, Antonio Ferronetti, Alfonso Canfora, Fabrizio Cardin, Antonio Giugliano, Francesco Guida, Antonio Braun, Melania Battaglini Ciciriello, Federica Tovecci, Giovanni Mastrobuoni and Bruno Amato

    Citation: BMC Surgery 2012 12(Suppl 1):S4

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

  17. Substantial progresses in the management of peripheral arterial disease (PAD) have been made in the past two decades. Progress in the understanding of the endothelial-platel...

    Authors: Bruno Amato, Rita Compagna, Gianni Antonio Della Corte, Giovanni Martino, Tommaso Bianco, Guido Coretti, Roberto Rossi, Antonio Braucci, Giovanni Aprea, Pio Zeppa, Alessandro Puzziello and Claudio Terranova

    Citation: BMC Surgery 2012 12(Suppl 1):S1

    Content type: Research article

    Published on:

    This article is part of a Supplement: Volume 12 Supplement 1

    The Retraction Note to this article has been published in BMC Surgery 2016 16:24

  18. Gastric cancer with synchronous liver metastasis remains a clinical treatment challenge. There has been a longstanding debate on the question whether surgical resection could be beneficial to long-term surviva...

    Authors: Yan-Na Wang, Kun-Tang Shen, Jia-Qian Ling, Xiao-Dong Gao, Ying-Yong Hou, Xue-Fei Wang, Jing Qin, Yi-Hong Sun and Xin-Yu Qin

    Citation: BMC Surgery 2012 12:20

    Content type: Research article

    Published on:

  19. Inguinal hernia is a common condition and its repair (herniorrhaphy) is one of the most commonly performed procedures in general surgery. The Lichtenstein herniorrhaphy technique is a widely used and effective...

    Authors: Rannie Rabe, Clarence Pio Rey Yacapin, Brian S Buckley and Jose Macario Faylona

    Citation: BMC Surgery 2012 12:19

    Content type: Research article

    Published on:

  20. Prophylactic antibiotics (PAs) are beneficial to breast cancer patients undergoing surgery because they prevent surgical site infection (SSI), but limited information regarding their use has been published. Th...

    Authors: Sergio A Acuna, Fernando A Angarita, Jaime Escallon, Mauricio Tawil and Lilian Torregrosa

    Citation: BMC Surgery 2012 12:18

    Content type: Research article

    Published on:

  21. In upper limb surgery, the pneumatic tourniquet is an essential tool to provide a clean, bloodless surgical field, improving visualization of anatomical structures and preventing iatrogenic failure. Optimal in...

    Authors: Junko Sato, Yoshinori Ishii, Hideo Noguchi and Mitsuhiro Takeda

    Citation: BMC Surgery 2012 12:17

    Content type: Research article

    Published on:

  22. This study was designed to identify risk factors for lymph node metastasis of early stage colorectal cancer, which was confirmed to a carcinoma that invaded the submucosa after radical resection.

    Authors: Bong-Hyeon Kye, Ji-Han Jung, Hyung-Jin Kim, Se-Goo Kang, Hyeon-Min Cho and Jun-Gi Kim

    Citation: BMC Surgery 2012 12:16

    Content type: Research article

    Published on:

  23. The incision used for thyroid surgery has become shorter over time, from the classical 10 cm long Kocher incision to the shortest 15 mm access achieved with Minimally Invasive Video-Assisted Thyroidectomy. Thi...

    Authors: Fabrizio Consorti, Francesca Milazzo, Mariagiovanna Notarangelo, Laura Scardella and Alfredo Antonaci

    Citation: BMC Surgery 2012 12:15

    Content type: Research article

    Published on:

  24. Patients having arthroscopic shoulder surgery frequently experience periods of inadvertent hypothermia. This common perioperative problem has been linked to adverse patient outcomes such as myocardial ischaemi...

    Authors: Jed Duff, Renatta Di Staso, Kerry-Anne Cobbe, Nicole Draper, Simon Tan, Emma Halliday, Sandy Middleton, Lawrence Lam and Kim Walker

    Citation: BMC Surgery 2012 12:14

    Content type: Study protocol

    Published on:

  25. Hydrocephalus following spontaneous aneurysmal sub-arachnoid hemorrhage (SAH) is often associated with unfavorable outcome. This study aimed to determine the potential risk factors and outcomes of shunt-depend...

    Authors: Yi-Min Wang, Yu-Jun Lin, Ming-Jung Chuang, Tsung-Han Lee, Nai-Wen Tsai, Ben-Chung Cheng, Wei-Che Lin, Ben Yu-Jih Su, Tzu-Ming Yang, Wen-Neng Chang, Chih-Cheng Huang, Chia-Te Kung, Lian-Hui Lee, Hung-Chen Wang and Cheng-Hsien Lu

    Citation: BMC Surgery 2012 12:12

    Content type: Research article

    Published on:

  26. To evaluate the quality of life (QOL) in relation to age, sex, clinical stage, postoperative complication, and adjuvant chemotherapy in patients who underwent curative total gastrectomy with D2 lymphadenectomy...

    Authors: Gintare Jakstaite, Narimantas Evaldas Samalavicius, Giedre Smailyte and Raimundas Lunevicius

    Citation: BMC Surgery 2012 12:11

    Content type: Research article

    Published on:

  27. Hepaticojejunostomy (HJ) is the classical reconstruction for benign biliary stricture. Endoscopic management of anastomotic complications after hepaticojejunostomy is extremely difficult. In this work we asses...

    Authors: Mostafa A Hamad and Hussein El-Amin

    Citation: BMC Surgery 2012 12:9

    Content type: Research article

    Published on:

  28. Communication breakdowns represent the main root cause of preventable complications which lead to harm to surgical patients. Standardized readbacks have been successfully implemented as a main pillar of profes...

    Authors: Hari Prabhakar, Jeffrey B Cooper, Allison Sabel, Sebastian Weckbach, Philip S Mehler and Philip F Stahel

    Citation: BMC Surgery 2012 12:8

    Content type: Research article

    Published on:

  29. To describe the rationale and design of an observational cohort study analyzing the effects of endoscopic Totally Extraperitoneal (TEP) hernia repair on male fertility (MAIN study).

    Authors: Nelleke Schouten, Thijs van Dalen, Niels Smakman, Sjoerd G Elias, Cees van de Water, Roan J Spermon, Laurens Sibinga Mulder and Ine P J Burgmans

    Citation: BMC Surgery 2012 12:7

    Content type: Study protocol

    Published on:

  30. Modern high-velocity projectiles produce temporary cavities and can thus cause extensive tissue destruction along the bullet path. It is still unclear whether gelatin blocks, which are used as a well-accepted ...

    Authors: Constantin von See, Majeed Rana, Marcus Stoetzer, Horst Kokemueller, Martin Ruecker and Nils-Claudius Gellrich

    Citation: BMC Surgery 2012 12:6

    Content type: Research article

    Published on:

  31. Five percent of all patients with breast cancer have distant metastatic disease at initial presentation. Because metastatic breast cancer is considered to be an incurable disease, it is generally treated with ...

    Authors: Jetske Ruiterkamp, Adri C Voogd, Vivianne CG Tjan-Heijnen, Koop Bosscha, Yvette M van der Linden, Emiel JTh Rutgers, Epie Boven, Maurice JC van der Sangen and Miranda F Ernst

    Citation: BMC Surgery 2012 12:5

    Content type: Study protocol

    Published on:

  32. Negative pressure wound therapy (NPWT) has gained acceptance among surgeons, for the treatment of open abdomen, since very high closure rates have been reported with this method, compared to other kinds of wou...

    Authors: Sandra Lindstedt, Malin Malmsjö, Johan Hansson, Joanna Hlebowicz and Richard Ingemansson

    Citation: BMC Surgery 2012 12:4

    Content type: Research article

    Published on:

  33. Ultrasonic scalpel (UC) and monopolar electrocautery (ME) are common tools for soft tissue dissection. However, morphological data on the related tissue alteration are discordant. We developed an automatic dev...

    Authors: Kia Homayounfar, Johanna Meis, Klaus Jung, Bernd Klosterhalfen, Thilo Sprenger, Lena-Christin Conradi, Claus Langer and Heinz Becker

    Citation: BMC Surgery 2012 12:3

    Content type: Research article

    Published on:

  34. A response to Seiler et al: Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541). Ann Surg 20...

    Authors: Lars Fischer, Hanns P Knaebel, Henriette Golcher, Thomas Bruckner, Markus K Diener, Jeannine Bachmann, Markus W Büchler and Christoph M Seiler

    Citation: BMC Surgery 2012 12:2

    Content type: Correspondence

    Published on:

  35. A beneficial effect of gentamicin supplemented mesh material on tissue integration is known. To further elucidate the interaction of collagen and MMP-2 in chronic foreign body reaction and to determine the sig...

    Authors: Marcel Binnebösel, Klaus T von Trotha, Christina Ricken, Christian D Klink, Karsten Junge, Joachim Conze, Marc Jansen, Ulf P Neumann and Petra Lynen Jansen

    Citation: BMC Surgery 2012 12:1

    Content type: Research article

    Published on:

  36. To examine commonly used scoring systems, designed to predict overall outcome in critically ill patients, for their ability to select patients with an abdominal sepsis that have ongoing infection needing relap...

    Authors: Oddeke van Ruler, Jordy JS Kiewiet, Kimberley R Boer, Bas Lamme, Dirk J Gouma, Marja A Boermeester and Johannes B Reitsma

    Citation: BMC Surgery 2011 11:38

    Content type: Research article

    Published on:

  37. Every surgical suture compresses the enclosed tissue with a tension that depends from the knotting force and the resistance of the tissue. The aim of this study was to identify the dynamic change of applied su...

    Authors: Christian D Klink, Marcel Binnebösel, Hamid P Alizai, Andreas Lambertz, Klaus T vonTrotha, Elmar Junker, Catherine Disselhorst-Klug, Ulf P Neumann and Uwe Klinge

    Citation: BMC Surgery 2011 11:36

    Content type: Research article

    Published on:

  38. Peritoneal dialysis (PD) is an effective treatment for end-stage renal disease. It allows patients more freedom to perform daily activities compared to haemodialysis. Key to successful PD is the presence of a ...

    Authors: Sander M Hagen, Arjan M van Alphen, Jan NM IJzermans and Frank JMF Dor

    Citation: BMC Surgery 2011 11:35

    Content type: Study protocol

    Published on:

  39. The CARTS study is a multicenter feasibility study, investigating the role of rectum saving surgery for distal rectal cancer.

    Authors: Guus MJ Bökkerink, Eelco JR de Graaf, Cornelis JA Punt, Iris D Nagtegaal, Heidi Rütten, Joost JME Nuyttens, Esther van Meerten, Pascal G Doornebosch, Pieter J Tanis, Eric J Derksen, Roy S Dwarkasing, Corrie AM Marijnen, Annemieke Cats, Rob AEM Tollenaar, Ignace HJT de Hingh, Harm JT Rutten…

    Citation: BMC Surgery 2011 11:34

    Content type: Study protocol

    Published on:

  40. Anastomotic or marginal ulcers occur in 0.6 to 16% of patients after laparoscopic Roux-en-Y-Gastric Bypass. Initial therapy aims at eliminating known risk factors including smoking, Helicobacter pylori infecti...

    Authors: Daniel C Steinemann, Marc Schiesser, Pierre-Alain Clavien and Antonio Nocito

    Citation: BMC Surgery 2011 11:33

    Content type: Case report

    Published on:

  41. Therapeutic strategies aiming to reduce ischemia/reperfusion injury by conditioning tissue tolerance against ischemia appear attractive not only from a scientific perspective, but also in clinics. Although pre...

    Authors: Robert Kraemer, Johan Lorenzen, Mohammad Kabbani, Christian Herold, Marc Busche, Peter M Vogt and Karsten Knobloch

    Citation: BMC Surgery 2011 11:32

    Content type: Research article

    Published on:

  42. Accidental or intentional subcutaneous and/or intramuscular injection of metallic mercury is an uncommon form of poisoning. Although it does not carry the same risk as mercury vapour inhalation, it may cause d...

    Authors: Joerg Friesenbichler, Werner Maurer-Ertl, Patrick Sadoghi, Elisabeth Wolf and Andreas Leithner

    Citation: BMC Surgery 2011 11:31

    Content type: Case report

    Published on:

  43. Many factors have been put forward as a driving mechanism of surgery-triggered adhesion formation (AF). In this study, we underline the key role of specific surgical trauma related with open surgery (OS) and l...

    Authors: Sergei V Pismensky, Zhomart R Kalzhanov, Marina Yu Eliseeva, Ioannis P Kosmas and Ospan A Mynbaev

    Citation: BMC Surgery 2011 11:30

    Content type: Research article

    Published on:

  44. Degenerative spinal stenosis and instability requiring multilevel spine surgery has been associated with large blood losses. Factors that affect perioperative blood loss include time of surgery, surgical proce...

    Authors: Stefan Endres, Martin Heinz and Axel Wilke

    Citation: BMC Surgery 2011 11:29

    Content type: Research article

    Published on:

  45. Obesity is a major public health problem in both developed and developing countries alike and leads to a series of changes in respiratory physiology. There is a strong correlation between obesity and cardiopul...

    Authors: Luis VF Oliveira, Isabella C Aguiar, Raquel P Hirata, Newton S Faria Junior, Israel S Reis, Luciana MM Sampaio, Claudia S Oliveira, Paulo TC Carvalho, Fernando SS Leitao Filho, Lilian C Giannasi, Lia Azevedo Pinto, Carlos Alberto Malheiros and Wilson Rodrigues Freitas Jr

    Citation: BMC Surgery 2011 11:28

    Content type: Study protocol

    Published on:

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