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Table 2 Univariate and Multivariate logistic regression analysis of the patients with colorectal cancer (CRC)

From: A prediction nomogram for perineural invasion in colorectal cancer patients: a retrospective study

Variable

Univariate analysis

Multivariate analysis

OR (95%CI)

P-value

OR (95%CI)

P-value

Age (years)

1.00(0.97–1.02)

0.828

  

BMI (Kg/m2)

0.93(0.83–1.06)

0.277

  

Gender Female

Reference

   

 Male

0.95(0.56–1.61)

0.836

  

Smoking NO

Reference

   

 YES

1.48(0.82–2.68)

0.189

  

CA125(KU/L) ≤ 35

Reference

   

  > 35

0.19(0.02–1.57)

0.123

  

CA199(KU/L) ≤ 35

Reference

   

  > 35

2.39(1.09–5.28)

0.030

  

CEA(ng/ml) ≤ 5

Reference

   

  > 5

2.25(1.29–3.92)

0.004

3.13(1.60–6.13)

0.001

TAP(um2) ≤ 121

Reference

   

  > 121

0.84(0.34–2.12)

0.718

  

LMR ≤ 2.76

Reference

   

  > 2.76

1.35(0.76–2.43)

0.308

  

PLR ≤ 136.98

Reference

   

  > 136.98

2.12(1.20–3.74)

0.009

2.07(1.08–3.96)

0.028

NLR ≤ 2.52

Reference

   

  > 2.52

2.01(1.12–3.60)

0.019

  

CT N-stage N0

Reference

   

 N1-N2

2.55(1.46–4.42)

0.001

3.44(1.74–6.80)

 < 0.001

CT T-stage T1-T2

Reference

   

 T3-T4

1.81(1.01–3.24)

0.047

  

Endoscopic biopsy

 Poorly

Reference

   

 Moderately

0.57(0.24–1.33)

0.192

0.69 (0.26–1.84)

0.457

 Well

0.10(0.02–0.45)

0.002

0.15 (0.03–0.74)

0.020

Pathological type

 adenocarcinoma

Reference

   

 non-adenocarcinoma

0.57(0.17–1.94)

0.365

  

Primary site

 Left colon

Reference

   

 Right colon

0.98(0.46–2.09)

0.960

0.79 (0.34–1.85)

0.593

 Rectum

2.79(1.49–5.22)

0.001

2.49 (1.21–5.12)

0.013

Tumor gross type

 Ulceration

Reference

   

 Infiltrative

0.81(0.19–3.45)

0.781

0.65 (0.14–2.91)

0.572

 Protruded

0.47(0.27–0.82)

0.008

0.42 (0.22–0.81)

0.010

 Other

1.63(0.28–9.33)

0.583

1.02 (0.16–6.66)

0.983