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Table 1 Clinicopathological characteristics and short-term outcomes in CRLM patients receiving simultaneous resection before PSM

From: An elevated preoperative cholesterol-to-lymphocyte ratio predicts unfavourable outcomes in colorectal cancer liver metastasis patients receiving simultaneous resections: a retrospective study

Item

CLR < 3.06

(n = 285)

CLR ≥ 3.06

(n = 159)

P

All patients

(n = 444)

Age ≥60 years, n (%)

126 (44.2%)

80 (50.3%)

0.216

206(46.4%)

Male, n (%)

185 (64.9%)

101 (63.5%)

0.769

286(64.4%)

BMI ≥ 24 kg/m2, n (%)

134 (47.0%)

75 (47.2%)

0.975

209(47.1%)

NLR ≥ 1.86, n (%)

113 (39.6%)

107 (67.3%)

< 0.001

220(49.5%)

Comorbidity, n (%)

123 (43.2%)

65 (40.9%)

0.641

188(42.3%)

ASA score 3–4, n (%)

30 (10.5%)

24 (15.1%)

0.158

54(12.2%)

Preoperative CEA ≥ 200 ng/ml, n (%)

10 ( 3.5%)

9 ( 5.7%)

0.283

19(4.3%)

Primary site in colon, n (%)

167 (58.6%)

85 (53.5%)

0.295

252(56.8%)

Right hemicolon, n (%)

53 (18.6%)

36 (22.6%)

0.307

89(20.0%)

Diameter of liver metastases ≥ 5 cm, n (%)

34 (11.9%)

29 (18.2%)

0.068

63(14.2%)

Multiple liver metastases, n (%)

168 (58.9%)

92 (57.9%)

0.824

260(58.6%)

Bilobar liver distribution, n (%)

108 (37.9%)

69 (43.4%)

0.256

177(39.9%)

Poor differentiation, n (%)

88 (30.9%)

56 (35.2%)

0.349

144(32.4%)

T3-T4 stage, n (%)

263 (92.3%)

146 (91.8%)

0.864

409(92.1%)

Positive lymph node metastasis, n (%)

206 (72.3%)

115 (72.3%)

0.992

321(72.3%)

Extrahepatic metastases, n (%)

30 (10.5%)

14 ( 8.8%)

0.561

44(9.9%)

Concomitant RFA, n (%)

25 ( 8.8%)

18 (11.3%)

0.384

43(9.7%)

R0 resection, n (%)

214 (75.1%)

119 (74.8%)

0.954

333(75.0%)

Major liver resection, n (%)

138 (48.4%)

76 (47.8%)

0.900

214(48.2%)

Pretreatment chemotherapy, n (%)

160 (56.1%)

93 (58.5%)

0.632

253(57.0%)

Hepatic portal occlusion, n (%)

192 (67.4%)

117 (73.6%)

0.172

309(69.6%)

All laparoscopic operation, n (%)

57 (20.0%)

40 (25.2%)

0.207

97(21.8%)

Operation time, min (median, IQR)

340.0(260.0-420.0)

320.0(270.0-430.0)

0.971

335.0(265.0-420.0)

Blood loss, ml (median, IQR)

200.0(100.0-400.0)

200.0(150.0-400.0)

0.163

200.0(100.0-400.0)

Blood transfusion, n (%)

66(23.2%)

37(23.3%)

0.979

103(23.2%)

Complications, n (%)

 

0, n (%)

149(52.3%)

77(48.4%)

0.335

226(50.9%)

1–2, n (%)

83(29.1%)

43(27.0%)

126(28.4%)

3–5, n (%)

53(18.6%)

39(24.5%)

92(20.7%)

Postoperative minor complications, n (%)

83(29.1%)

43(27.0%)

0.641

126(28.4%)

Postoperative major complications, n (%)

53(18.6%)

39(24.5%)

0.139

92(20.7%)

ICU, n (%)

22(7.7%)

13(8.2%)

0.864

35(7.9%)

Post-operative hospital stay, days (median, IQR)

10.0(9.0–13.0)

10.0(8.0–14.0)

0.453

10.0(9.0–13.0)