Skip to main content

Table 1 Baseline characteristics

From: Preoperative aspartate aminotransferase to albumin ratio correlates with tumor characteristics and predicts outcome of hepatocellular carcinoma patients after curative hepatectomy: a multicenter study

Variables

All

Low-risk group

Intermediate-risk group

High-risk group

p value

n = 991

n = 323

n = 514

n = 154

Age (> 60 years)

231 (23.3)

71 (22.0)

124 (24.1)

36 (23.4)

0.775

Gender (male, %)

830 (83.8)

273 (84.5)

429 (83.5)

128 (83.1)

0.897

Diabetes

131 (13.2)

51 (15.8)

59 (11.5)

21 (13.6)

0.198

HBsAg

942 (95.1)

300 (92.9)

492 (95.7)

150 (97.4)

0.063

HBeAg

218 (22.0)

42 (13.0)

135 (26.3)

41 (26.6)

 < 0.001

HBV-DNA (> 103 IU/mL)

575 (58.0)

130 (40.2)

324 (63.0)

121 (78.6)

 < 0.001

Cirrhosis

821 (82.8)

263 (81.4)

432 (84.0)

126 (81.8)

0.578

Tumor size (cm)

4.5 [3.0, 7.5]

4.0 [2.8, 5.5]

5.0 [3.0, 7.5]

8.1 [4.6, 12.0]

 < 0.001

Multiple tumors

89 (9.0)

25 (7.7)

52 (10.1)

12 (7.8)

0.430

MVI

227 (22.9)

43 (13.3)

133 (25.9)

51 (33.1)

 < 0.001

Capsular invasion

436 (44.0)

136 (42.1)

228 (44.4)

72 (46.8)

0.615

Satellite lesion

102 (10.3)

26 (8.0)

60 (11.7)

16 (10.4)

0.244

Tumor differentiation

    

0.704

 Well

14 (1.4)

5 (1.5)

6 (1.2)

3 (1.9)

 

 Moderate

534 (53.9)

183 (56.7)

271 (52.7)

80 (51.9)

 

 Poorly

443 (44.7)

135 (41.8)

237 (46.1)

71 (46.1)

 

AFP (> 400 ng/mL)

376 (37.9)

103 (31.9)

197 (38.3)

76 (49.4)

0.001

INR

1.04 [1.00, 1.10]

1.03 [0.98, 1.08]

1.04 [1.00, 1.10]

1.07 [1.01, 1.14]

 < 0.001

BCLC staging

    

0.900

 0

64 (6.4)

30 (9.3)

29 (5.6)

5 (3.2)

 

 A

858 (86.6)

276 (85.4)

442 (86.0)

140 (9.0)

 

 B

69 (7.0)

17 (5.3)

43 (8.4)

9 (5.8)

 

PLR (> 103.5)

382 (38.5)

114 (35.3)

183 (35.6)

85 (55.2)

 < 0.001

NLR (> 2.6)

327 (33.0)

91 (28.2)

167 (32.5)

69 (44.8)

0.001

ALT (> 40 IU/L)

403 (40.7)

38 (11.8)

239 (46.5)

126 (81.8)

 < 0.001

TBIL (> 17.1 μmol/L)

40 (4.0)

8 (2.5)

14 (2.7)

18 (11.7)

 < 0.001

CREA (μmol/L)

69.0 [60.0, 80.0]

72.0 [63.0, 82.0]

69.0 [60.0, 80.3]

65.0 [57.5, 74.8]

 < 0.001

  1. MVI microvascular invasion; AFP α-fetoprotein; PLR platelet-to-lymphocyte ratio; NLR neutrophil-to-lymphocyte ratio; ALT alanine aminotransferase; TBIL total bilirubin; CREA creatinine
Back to article page

BMC Surgery

ISSN: 1471-2482

Contact us