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Table 4 Recurrence rate and clinicopathological findings of patient stratified for different ages

From: The role of prophylactic central compartment lymph node dissection in elderly patients with differentiated thyroid cancer: a multicentric study

 

Age 65–74 (n = 298)

Age 75+ (n = 73)

p Value

Central neck recurrence

12 (4%)

6 (8.2%)

0.135

Lateral recurrence

11 (3.6%)

4 (5.4%)

0.486

Histologic Features:

 • Mean tumor size (mm)

17 ± 11

22 ± 5

0.513

 • Microcarcinoma

98 (32.8%)

16 (21.9%)

0.068

 • Unifocal

276 (92.6%)

62 (84.9%)

< 0,001*

 • Multifocal

22 (7.3%)

11 (15%)

< 0,001*

pTNM stage

 • I

280 (93.9%)

54 (73.9%)

< 0.001*

 • II

15 (5%)

12 (16.4%)

< 0.001*

 • III

3 (1%)

7 (9.5%)

< 0.001*

Complications (All patients)

 • Temporary hypoparathyroidism

34 (11.4%)

18 (24.6%)

0.003*

 • Permanent hypoparathyroidism

1 (0.33%)

2 (2.7%)

0.039*

 • Recurrent nerve injury

6 (2%)

7 (9.5%)

0.001*

Complications (Group A - TT)

 • Temporary hypoparathyroidism

12/152 (7,8%)

6/32 (18,7%)

0.060

 • Permanent hypoparathyroidism

0/152 (0%)

0/32 (0%)

NA

 • Recurrent nerve injury

2/152 (1,3%)

3/32 (9,7%)

0.010*

Complications (Group B – TT+ PCLD)

 • Temporary hypoparathyroidism

22/146 (15%)

12/41 (29,2%)

0.037

 • Permanent hypoparathyroidism

1/146 (0,6%)

2/41 (4,8%)

0.059

 • Recurrent nerve injury

4/146 (2,7%)

4/41 (9,7%)

0.049*

  1. *Statistically significant