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Perineal pseudocontinent colostomy is safe and efficient technique for perineal reconstruction after abdominoperineal resection for rectal adenocarcinoma
© Souadka et al.; licensee BioMed Central. 2015
Received: 26 June 2014
Accepted: 23 March 2015
Published: 10 April 2015
The aim of this study was to evaluate oncologic results and satisfaction rate results of pseudocontinent perineal colostomy (PCPC) using Schmidt’s technique in patients undergoing abdominoperineal resection (APR) for managing low rectal adenocarcinoma.
From January 1993 and December 2007, One hundred and forty six patients underwent successfully PCPC after abdominoperineal resection for lower rectal adenocarcinoma. There were 75 women, with an average age of 47 years old. All patients received neoadjuvant radiotherapy with or without chemotherapy. Long-term oncological results and satisfaction rate were evaluated.
After a median follow up of 36 months (range 12–156) months, the five-year overall survival and disease free survival rate were 74.6% and 60.3% respectively. Local and distant recurrences occurred respectively in 10 (6,8%) and 29 (20%) patients. Seventy-seven percent (77%) of the patients were highly satisfied with this technique and only one patient was unsatisfied. However, none of them accepted the conversion to an abdominal colostomy neither would have changed PCPC for an iliac colostomy at first intent.
This study showed that pseudocontinent perineal colostomy is a safe and reliable pelvic reconstruction technique after abdominoperineal resection for low rectal adenocarcinoma. It provides high degree of patient satisfaction without compromising oncological results. It is a good option in selected patients, especially in Muslim countries.
The management of ultra-low rectal cancer less than 2 cm from the dentate line is still challenging. The only two procedures available are an abdominoperineal resection (APR) with definitive iliac colostomy and intersphincteric resection (ISR) with a coloanal anastomosis. However ISR oncological and functional results are still debatable, the reason why APR remains the gold standard technique when both internal and external sphincter are involved.
Perineal pseudocontinent colostomy (PCPC) is a reconstruction technique performed after APR, in which the permanent colostomy is placed in the perineum instead of left low quadrant of the abdomen . In this procedure, a graft of smooth colonic muscle tightly surrounds the lowered colon. This technique was first described by Schmidt , for abdominal colostomies, and then applied by Gamagami to the perineum . It was encouraged by the fact that it offers two major advantages: preservation of the body image by invisible perineal placement, improving the quality of life of these patients , and a reasonable continence with acceptable functional results [3,5-7]. Since previous studies reported that abdominal colostomy is associated with a negative impact on the quality of life [8-10], especially in Muslim patients , this technique could be a very interesting for these patients .
The main concern about PCPC in all previous published studies was only its promising functional results [3-7,13-16]. Only Goere and al reported oncological outcomes of PCPC after APR for 19 anal epidermoid carcinoma.
The aim of this study was to evaluate long-term oncologic results and patients satisfaction of PCPC using Schmidt technique in Moroccan patients undergoing APR for managing lower rectal adenocarcinoma.
From 1993 to 2007, 380 APRs for low rectal adenocarcinomas were performed in the Department of Surgical Oncology in both the National Institute of Oncology and the Al Azhar Oncological Center in Rabat, Morocco. Both surgical oncology departments of the institutions cited above granted permission to access data of included patients for the purpose of this study. The medical ethical comity of both institutions approved this study.
The design of this study, indications and functional results of patients with PCPC were already published in previous publication . One hundred forty six patients underwent successful perineal reconstruction by PCPC.
Colonic irrigations are started from the third day according to the protocol previously reported . Patients and one of their family members are daily educated and assisted while performing colonic irrigations by specialized nurses.
Assessment of oncological results and satisfaction score
Patients were first seen and examined by their own surgeons every 3 weeks till the complete healing of the wound. Then Follow-up, which included a clinical examination, a stoma examination and a liver ultrasound or abdomino-pelvic CT (alternately), was performed every three to 4 months for two years, every six months for three years and then once a year. A postoperative recurrence was stated by biopsy proven or radiographic evidence of recurrent disease. Survival was analysed according to Kaplan-Meier method using the IBM Corp. Released 2011. IBM SPSS Statistics for Macintosh, Version 20.0. Armonk, NY: IBM Corp. In all previous study of PCPC, Continence results were usually evaluated according to Kirwan continence scale . Subjective satisfactory score was determined by asking patients to rate their satisfaction according to a scale from 0 to 10 (unsatisfied 0–3; moderately satisfied 4–7; satisfied 8–10) and to answer two open questions: Do you want to convert perineal colostomy to abdominal colostomy? If you had the choice again, would you choose PCPC or abdominal colostomy at primary intention?
71 M/75 F
Mean age ± SD (years)
47 ± 10,4 (21–76)
Posterior pelvic exenteration
In second step (after LQIC)
• Alone (before 2000)
• Combined to chemotherapy
Tumour stage (UICC)
details of satisfaction rate, functional and oncologicial results of 146 PCPC
Kirwan stage of continence
• A and B
• C, D and E
Satisfaction rate at the latest visit
• Highly satisfied (8–10)
• Satisfied (4–7)
• Unsatisfied (0–3)
• Median follow up of months
36 months (range 12–156)
• 5-year Overall survival rate
• 5-year disease free survival
All pelvic recurrences were diagnosed after digital examination of the perineal stoma. Median delay of local recurrences was 18,5 months (ranging from 13 to 66). Two patients had both pelvic recurrences and liver metastases and were treated by chemotherapy. All other patients had conversion to iliac colostomy after surgical excision of the recurrence except one who refused.
Distant Recurrences were treated with systemic chemotherapy. Liver metastases occurred in 20 (13,7%) patients. There were combined to lung and bone metastases respectively in 4 and one patient. Thirteen patients had only liver metastases and 5 of them were resected. Three (2,1%) patients had peritoneal carcinomatosis and one exclusive bone metastases treated by radiotherapy.
One hundred twelve (77%) patients were highly satisfied of this technique and 33 (22,4%) were moderately satisfied. Moreover, none of these patients accepted a conversion to abdominal colostomy even the unsatisfied 72 years woman (first open question). And as an answer to the second question: none of them would choose abdominal colostomy at first intent.
This study is the largest series of pseudocontinent perineal colostomy for rectal adenocarcinoma in the literature, showing that it is oncologically safe and provides high satisfaction rate.
Local and distant recurrences occurred in respectively 6,8% and 20% of the patients with an overall and disease free and five year survival rate of respectively 74,6% and 60,3%.
These results are comparable to classic APR with primary perineal closure in the literature [18-20], since PCPC is only a pelvic reconstruction after rectal resection respecting the rules of oncologic surgery. Moreover, the main theoretical oncological advantage of this technique is to allow an early diagnosis of pelvic recurrences by rectal examination or by echo-endoscopy [14,21], as the case of our study, all local recurrences were detected by clinical rectal inspection and confirmed by histological findings before starting adequate treatment.
Functional results of CPC are good with a high kirwan score (stage A and B) in 68% of the cases with no need to wear pads and no soiling . More over, 77% of the patients were highly satisfied and none of them regretted the choice of this alternative to abdominal colostomy.
Many authors reported that permanent iliac colostomy could significantly alter patients’ quality of life by affecting negatively physical, sexual, social, and psychological aspects of life [8-10,22]. Cakmak and al demonstrated that social and sexual aspects of life are also affected in spouses of patients with colostomies . Since 80% of patients reported that the reason for their inactive sexual life was their spouse’s abdominal colostomy, which they found repulsive . Kuzu et al. showed that social, physical, sexual, and psychological aspects of life, in addition to religious worship, are severely impaired by sphincter sacrificing surgery in the Islamic population . Indeed, daily praying and fasting were altered, since significantly greater number of Muslim who underwent APR stopped daily praying and did not fast during Ramadan . In Islamic societies, religious rituals are considered as an important factor of social adaptation and improved quality of life.
In our study, we proposed the PCPC technique to our patients believing that it would be more adapted to their economic situation, social and religious specificities of our population. By allowing body image preservation, PCPC makes easy the social reinsertion and avoids the alteration of quality of life due to permanent iliac colostomy, especially in Muslim patients. These reasons could explain the high rate of satisfaction among our patients.
Several techniques of anal sphincter reconstruction and perineal closure have been described: myocutanus flaps as RAM flap to cover a large skin defect; artificial sphincter  or nearby skeletal muscles including gracilis, gluteus maximus or adductor longus muscle [24-26], with or without electrical stimulator transposed around the PCPC  to increase the continence of the neosphincter; more recently the combination of both RAM flap and PCPC  or . However, PCPC remains a simpler technique, easy to learn, that may be performed routinely after every APR in selected patients. It is performed by the same perineal incision, less costly to achieve with no need to apply any other synthetic material.
This study has some limitations, by its retrospective aspect and large period studied, we weren’t able to descibe more details about to pathological assessement, quality of mesorectal excition and lateral margins . Furthermore, our assessement of satisfaction was subjective and the use of QOL questionnary as (EORTC) would be more helpful. Further investigation related to specific impact of PCPC on muslim population should be done by comparing APR combined to abdominal colostomy to those with PCPC compared in two different groups according to their religions.
To our knowledge and by the time of writing this article, this is the largest study of patients who have undergone perineal colostomy for lower rectal adenocarcinoma that assessed the oncological results and subjective satisfaction rate of this technique. It allows good functional results without compromising oncological safety. Based on our data, we recommend the use of PCPC for perineal reconstruction in selected patients after APR for very low rectal adenocarcinoma, especially for Muslim patients.
This study shows that pseudocontinent perineal colostomy is a simple, safe and reliable pelvic reconstruction technique after abdominoperineal resection for lower rectal adenocarcinoma. It provides a high degree of patient satisfaction without compromising oncological results. It is a good option in selected patients especially in the muslim and low-income countries population.
Authors would like to thank Dr Dumont F for the great help writing this manuscript and Miss Benkhouya H for her support.
- Lasser P. Continent colostomy or pseudo-continent colostomy. J Chir. 2002;139:274–7.Google Scholar
- Schmidt E, Bruch HP. Autotransplantation of smooth muscle for treating incontinence of sphincters (author’s transl). J Chir. 1981;118:315–20.Google Scholar
- Gamagami RA, Chiotasso P, Lazorthes F. Continent perineal colostomy after abdominoperineal resection: outcome after 63 cases. Dis Colon Rectum. 1999;42:626–30. discussion 630–621.View ArticlePubMedGoogle Scholar
- Pocard M, Sideris L, Zenasni F, Duvillard P, Boige V, Goere D, et al. Functional results and quality of life for patients with very low rectal cancer undergoing coloanal anastomosis or perineal colostomy with colonic muscular graft. Eur J Surg Oncol. 2007;33:459–62.Google Scholar
- Elias D, Lasser P, Leroux A, Rougier P, Comandella MG, Deraco M. Pseudo-continent perineal colostomies after amputation of the rectum for cancer. Gastroenterol Clin Biol. 1993;17:181–6.Google Scholar
- Goere D, Bonnet S, Pocard M, Deutsch E, Lasser P, Elias D. Oncologic and functional results after abdominoperineal resection plus pseudocontinent perineal colostomy for epidermoid carcinoma of the anus. Dis Colon Rectum. 2009;52:958–63.Google Scholar
- Souadka A, Majbar MA, Bougutab A, El Othmany A, Jalil A, Ahyoud FZ, et al. Risk factors of poor functional results at 1-year after pseudocontinent perineal colostomy for ultralow rectal adenocarcinoma. Dis Colon Rectum. 2013;56:1143–8.Google Scholar
- Engel J, Kerr J, Schlesinger-Raab A, Eckel R, Sauer H, Holzel D. Quality of life in rectal cancer patients: a four-year prospective study. Ann Surg. 2003;238:203–13.Google Scholar
- Guren MG, Eriksen MT, Wiig JN, Carlsen E, Nesbakken A, Sigurdsson HK, et al. Quality of life and functional outcome following anterior or abdominoperineal resection for rectal cancer. Eur J Surg Oncol. 2005;31:735–42.Google Scholar
- Pachler J, Wille-Jorgensen P. Quality of life after rectal resection for cancer, with or without permanent colostomy. Cochrane Database of Systematic Reviews. 2005; (2) CD004323.DOI: 10.1002/14651858.Google Scholar
- Kuzu MA, Topcu O, Ucar K, Ulukent S, Unal E, Erverdi N, et al. Effect of sphincter-sacrificing surgery for rectal carcinoma on quality of life in Muslim patients. Dis Colon Rectum. 2002;45:1359–66.Google Scholar
- Souadka A, Souadka A. Perineal morbidity and functional results of pseudocontinent perineal colostomy for low rectal cancer surgery: retrospective study of 149 cases. J Clin Oncol. 2012;30:2012.Google Scholar
- Lasser P, Dube P, Guillot JM, Elias D. Pseudo-continent perineal colostomy. Results and techniques. J Chir. 1997;134:174–9.Google Scholar
- Lasser P, Dube P, Guillot JM, Elias D. Pseudocontinent perineal colostomy following abdominoperineal resection: technique and findings in 49 patients. Eur J Surg Oncol. 2001;27:49–53.Google Scholar
- Berrada S, Khaiz D, Alloubi I. Pseudocontinent perineal colostomy. Ann Chir. 2005;130:15–20.View ArticlePubMedGoogle Scholar
- Kirzin S, Lazorthes F, Nouaille de Gorce H, Rives M, Guimbaud R, Portier G. Benefits of perineal colostomy on perineal morbidity after abdominoperineal resection. Dis Colon Rectum. 2010;53:1265–71.Google Scholar
- Kirwan WO, Turnbull Jr RB, Fazio VW, Weakley FL. Pullthrough operation with delayed anastomosis for rectal cancer. Br J Surg. 1978;65:695–8.Google Scholar
- Law WL, Chu KW. Impact of total mesorectal excision on the results of surgery of distal rectal cancer. Br J Surg. 2001;88:1607–12.View ArticlePubMedGoogle Scholar
- Silberfein EJ, Kattepogu KM, Hu CY. Long-term survival and recurrence outcomes following surgery for distal rectal cancer. Ann Surg Oncol. 2010;17:2863–9.View ArticlePubMedPubMed CentralGoogle Scholar
- Wibe A, Syse A, Andersen E, Tretli S, Myrvold HE, Soreide O. Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection. Dis Colon Rectum. 2004;47:48–58.Google Scholar
- Souadka A, Majbar MA. Perineal colostomy may be the solution of phantom rectum syndrome following abdominoperineal resection for rectal cancer. J Wound Ostomy Continence Nurs. 2014;41:15–6.View ArticlePubMedGoogle Scholar
- Cakmak A, Aylaz G, Kuzu MA. Permanent stoma not only affects patients’ quality of life but also that of their spouses. World J Surg. 2010;34:2872–6.View ArticlePubMedGoogle Scholar
- Christiansen J, Sparso B. Treatment of anal incontinence by an implantable prosthetic anal sphincter. Ann Surg. 1992;215:383–6.View ArticlePubMedPubMed CentralGoogle Scholar
- Wee JT, Wong CS. Functional anal sphincter reconstruction with the gracilis muscle after abdominoperineal resection. Lancet. 1983;2:1245–6.View ArticlePubMedGoogle Scholar
- Fedorov VD, Odaryuk TS, Shelygin YA. Results of radical surgery for advanced rectal cancer. Dis Colon Rectum. 1989;32:567–71.View ArticlePubMedGoogle Scholar
- Madoff RD, Rosen HR, Baeten CG, LaFontaine LJ, Cavina E, Devesa M, et al. Safety and efficacy of dynamic muscle plasty for anal incontinence: lessons from a prospective, multicenter trial. Gastroenterology. 1999;116:549–56.Google Scholar
- Abercrombie JE, Williams NS. Total anorectal reconstruction. Br J Surg. 1995;82:438–42.View ArticlePubMedGoogle Scholar
- Nassar OA. Modified pseudocontinent perineal colostomy: a special technique. Dis Colon Rectum. 2011;54:718–28.View ArticlePubMedGoogle Scholar
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