- Meeting abstract
- Open Access
Simultaneous surgical treatment of liver metastases from colorectal cancer in the elderly through Habib's technique
© Dumani et al; licensee BioMed Central Ltd. 2013
- Published: 16 September 2013
- Liver Metastasis
- Simultaneous Treatment
- Biliary Leak
- Minimal Blood Loss
- Synchronous Liver Metastasis
The liver is the most common site of metastasis from colo-rectal cancer (CRC) that may already be present up to 30% of cases the diagnosis of the primary tumor. In recent years, thanks to the improvement of surgical techniques and chemotherapy, the prognosis is improved and the criteria for a correct indication for surgery are less restrictive than in the past . The behaviour in the presence of synchronous liver metastases (ME), however, is still controversial, and removal of the primary tumor and ME can occur at different times. In view of the improvement of surgical techniques and perioperative management of technological development, in some selected cases a contemporary approach can be planned. We have thus decided to conduct a retrospective study to evaluate whether there is increased risk of morbidity 'and mortality, as well as a significant increase in operative time, especially focusing on the influence of age in the simultaneous treatment of the primary tumor and ME.
From 2004 to 2012, we treated 36 patients (23 males and 13 females) affected by CRC with liver metastases at diagnosis. We divided the patients into two groups:
Group A (21 patients) aged less than 70 y.o. (range 48-70) - M: F = 1:2
Group B (15 patients) > 70 years y.o. (range 71 - 84 years) - M: F = 1:3
Simultaneous treatment was based on the following inclusion criteria: patient's general health status, ASA score, characteristics of liver metastases (site, size and number) and percentage of healthy liver 3. Pre-operative investigations were blood tests, liver function test, colonoscopy, US abdomen, abdomen and pelvis CT scan or total body CT/PET, MRI, contrast-enhanced liver US and rectal endoscopic ultrasonography (for rectal cancer).
The patients were all operated on colectomy and liver metastases resection. Metastasectomies were always performed through Habib's technique which includes the activation of a bipolar device using radiofrequency 4.
Intra-operative blood loss, operative time, postoperative course, morbidity and mortality rates, hospitalization time were analysed and compared between two groups.
Results according to the different ages
Intra-operative blood loss (cc)
Increase of operative time (minutes)
Mean hospitalization time (days)
120 ml (range 80-320 cc)
160 ml (range 100-350 cc)
Habib’s device allowed us to perform metastasecomies at the same time of colectomy without Pringle’s manoeuvre, with minimal blood loss and without excessive prolongation of the surgical time 5. In both groups postoperative haemorrhage and biliary leak were minimal, supporting the effectiveness of the technique. Our experience showed that Habib’s procedure is easy and safe 6. It is our opinion that such device allows liver resections to be carried out with minimal blood loss and low mortality and morbidity rates, and results are similar between young and old patients.
- Weber Jean-Christophe, Navarra Giuseppe, Jiao Long R, Nicholls Joanna P, Jensen Steen Lindkaer, Habib Nagy A: New Technique for Liver Resection Using Heat Coagulative Necrosis. Annals of Surgery. 2002, 236 (5): 560-563. 10.1097/00000658-200211000-00004.PubMed CentralView ArticlePubMedGoogle Scholar
- Weber JC, Navarra G, Habib NA, Bachellier P, Jaeck D: Laparoscopic radiofrequency–assisted liver resection. Surg Endosc. 2003, 17: 831-834. 10.1007/s00464-002-4537-2.View ArticleGoogle Scholar
- Rispoli C, Rocco N, Iannone L, Amato B: Developing guidelines in geriatric surgery: role of the grade system. BMC Geriatrics. 2009, 9 (SUPPL.1): A99.Google Scholar
- Ayav Ahmet, Navarra Giuseppe, Habib Nagy A, Jiao Long R: New Technique for Liver Resection Using Heat Coagulative Necrosis. Annals of Surgery. 2005, 242 (5):Google Scholar
- Stavrou GA, Tzias Z, von Falck C, Habib N, Oldhafer KJ: Hepatic resection using heat coagulative necrosis. First report of successful trisegmentectomy after hypertrophy induction. Langenbecks Arch Surg. 2007, 392 (1): 95-97. 10.1007/s00423-006-0118-5.View ArticlePubMedGoogle Scholar
- Mastromarino R, D’Angelo S, Saglioccolo A, Rizzo G, Tammaro V, Carlomagno N, Renda A: Preliminary results with habib’s procedure. BMC Geriatrics. 2011, 11 (Suppl 1): A32-10.1186/1471-2318-11-S1-A32.PubMed CentralView ArticleGoogle Scholar
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