Table 1 Details of the included articles
Study | Surgery | Year | Race | Planned sample size | Number randomized | Case (T/C, n) | No. of drop-outs | Intervention | Control |
|---|---|---|---|---|---|---|---|---|---|
Uwiera et al. | Thyroidectomy | 2005 | Canada | - | 56 | 26/30 | 0 | Tisseel FS | No FS |
S Sözen et al. | Thyroidectomy | 2011 | Turkey | 100 | 100 | 50/50 | 0 | CryoSeal FS | With suction drain |
Kim et al. | Thyroidectomy and central neck dissection | 2012 | South Korea | 72 | 78 | 38/40 | 0 | Berplast P FS | No FS |
Hornig et al. | Thyroidectomy | 2016 | USA | 110 | 70 | 28/27 | 15 | Evicel FS | Saline Placebo |
Vidal-Pérez et al. | Thyroidectomy and neck dissection | 2016 | Spain | 60 | 60 | 30/30 | 0 | Tissucol FS | No FS |
Geraci et al. | Thyroidectomy | 2019 | Italy | 262 | 262 | 134/128 | 0 | Tisseel FS | With suction drain |
Eun Ju Ha et al. | Thyroidectomy and neck dissection | 2022 | South Korea | 41 | 41 | 20/21 | 0 | 6 mL tisseel FS | 2 mL tisseel FS |