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Table 4 Pathologic examination, stage and follow-up and adjuvant therapy

From: Retrospective analysis of the incidence of appendiceal neoplasm and malignancy in patients treated for suspected acute appendicitis

Pathology

Age (years)

Mean age

Sex

Incidence

Stage

Diagnostics during follow-up

Adjuvant therapy

Low-grade mucinous appendiceal neoplasia (LAMN, n = 3)

32

51.3

M

0.7%

pTis R0

sonography after 6 months

 

62

 

F

 

pT4a pM0, Stadium IIB

diagnostic laparoscopy

 

60

 

F

 

pTis

colonoscopy and diagnostic laparoscopy

 

Sessile serrated adenoma of the appendix (n = 3)

28

35.7

F

0.7%

no dysplasia

no follow-up

 

39

 

F

 

no dysplasia

no follow-up

 

40

 

F

 

no dysplasia

colonoscopy

 

Neuroendocrine tumours (n = 7)

20

39.3

M

1.5%

pT3 pNx V0 L0 Pn0 G1 R1

 

right hemicolectomy

41

 

M

 

pT3a L0 V0, G1

 

right hemicolectomy

27

 

M

 

pT4 L1 V0 Pn0 RX

DOTATATE-PET-CT, gastroscopy, colonoscopy, diagnostic laparoscopy and biopsy

 

50

 

M

 

pT4 pN2 (4/17) pM1b (PER) L1 V0 Pn0 G1 R0

DOTATATE-PET-CT

simultaneous right hemicolectomy, partial resection omentum majus, peritonectomy, palliative treatment

24

 

M

 

pT1 pNx L0 V0 Pn0 G1 R0

DOTATATE-PET-CT

 

52

 

F

 

pT1 pNx L0 V0 Pn0 G1 R0

no follow-up

 

61

 

M

 

pT1 pNx L0 V0

no follow-up

 

Appendiceal adenocarcinoma from intestinal type (n = 3)

90

74.0

F

0.7%

pT4b pN1b (2/17) L1 V0 Pn0 G2 R1

Exitus letalis (septic shock)

simultaneous right hemicolectomy

69

 

F

 

pT3 pNx L0 V0 Pn0 G2 R1

 

palliative chemotherapy

63

 

M

 

pT4a pNx L1 V0 Pn1 G2 R0

 

hemicolectomy, lymphadenectomy and adjuvant chemotherapy proposed, but not applied due to poor general condition and patient refusal

Goblet cell carcinoma (n = 1)

54

 

F

 

pT3 pN0 (0/10) L0 V0 Pn1 G2 R0

CT-scan and colonoscopy

right hemicolectomy a few weeks later, bilateral ovarectomy during follow-up