Table 4 Univariable and multivariable Cox proportional hazards regression analysis for PFS and OS in the matched cohort
Variables | PFS | OS | ||||||
|---|---|---|---|---|---|---|---|---|
Univariable | Multivariable | Univariable | Multivariable | |||||
Median PFS (mo) | P | HR (95% CI) | P | Median OS (mo) | P | HR (95% CI) | P | |
Sex | 0.505 | 0.870 | ||||||
Male | 3 | 24 | ||||||
Female | 5 | 21 | ||||||
Age | 0.275 | 0.239 | ||||||
≤60 | 4 | 24 | ||||||
>60 | 3 | 25 | ||||||
Primary tumor site | 0.054 | 1.59 (0.80, 3.18) | 0.186 | 0.077 | 1.31 (0.62, 2.74) | 0.480 | ||
Colon | 6 | 31 | ||||||
Rectum | 2 | 10 | ||||||
Grade | 0.437 | < 0.001 | 1.06 (0.13, 8.82) | 0.959 | ||||
G1 and G2 | 5 | 62 | ||||||
G3 | 3 | 10 | ||||||
Differentiation | 0.048 | 1.68 (0.85, 3.33) | 0.136 | < 0.001 | 5.14 (0.68–38.79) | 0.112 | ||
NET | 9 | 62 | ||||||
NEC | 2 | 9 | ||||||
Clinical T stage | 0.656 | 0.589 | ||||||
T1, T2 | 9 | 62 | ||||||
T3, T4 | 4 | 24 | ||||||
Clinical N stage | 0.873 | 0.263 | ||||||
N0 | 5 | 62 | ||||||
N1 | 4 | 24 | ||||||
Site of metastasis | 0.735 | 0.130 | ||||||
Single-organ | 4 | 32 | ||||||
Multiple-organ | 4 | 18 | ||||||
PTR | 0.613 | 0.983 | ||||||
Yes | 4 | 24 | ||||||
No | 4 | 31 | ||||||