Table 4 Results of the multivariate Cox-regression models
Category | Variable | Sub variable | Hazard Ratio | 95% Confidence Interval | p-value |
|---|---|---|---|---|---|
Demographic | Sex | Female | 0.97 | [0.59;1.60] | 0.912 |
Age | 1.03 | [1.00;1.06] | 0.077 | ||
ASA score | 1.68 | [1.03;2.74] | 0.039 | ||
Body mass index | 0.97 | [0.91;1.03] | 0.357 | ||
Charlson Comorbidity Index | 1.16 | [1.02;1.33] | 0.028 | ||
Smoking | Current smoker | 1.33 | [0.75;2.37] | 0.332 | |
Alcohol | 1–21 drinks/week | 1.50 | [0.46;4.94] | 0.503 | |
> 21 drinks/week | 2.33 | [0.37;14.86] | 0.369 | ||
Perioperative | Procedure time | 1.00 | [0.99;1.00] | 0.540 | |
Epidural analgesia | 1.39 | [0.38;5.04] | 0.619 | ||
Type of anesthesia§ | Intravenous and inhalation | 0.70 | [0.32;1.51] | 0.365 | |
Perioperative blood transfusion | 2.53 | [1.32;4.87] | 0.005 | ||
Tumor related | Preoperative chemotherapy | 0.77 | [0.25;2.35] | 0.645 | |
Postoperative chemotherapy | 0.53 | [0.29;0.96] | 0.035 | ||
Type of resection* | Total Pancreatectomy, TP | 1.69 | [0.67;4.26] | 0.269 | |
Pancreaticoduodenectomy, PD | 0.79 | [0.33;1.89] | 0.593 | ||
Tumor T stage# | T2 | 2.48 | [0.51;12.09] | 0.261 | |
T3 | 4.15 | [0.89;19.32] | 0.070 | ||
T4 | 1.68 | [0.18;15.72] | 0.649 | ||
Tumor N stage** | N1 | 2.76 | [1.35;5.63] | 0.005 | |
N2 | 4.12 | [1.69;10.02] | 0.002 | ||
Resection margin | R1 | 1.10 | [0.64;1.90] | 0.737 |