Table 1 Characteristics of included studies
First author (year) | Country | No. of Patients (M/F) | Age (years) | Intervention group (n) | Control group (n) | Treatment time |
|---|---|---|---|---|---|---|
Afghani (2018) | Iran | 60 (26/34) | 59.85 ± 8.12 | Methylprednisolone (125 mg, n = 30) | Blank control (n = 30) | At the end of esophagogastric anastomosis |
Gao (2017) | China | 90 (47/43) | Intervention group: 59.3 ± 3.2 Control group: 59.6 ± 3.6 | Prednisone (10 mg/kg, n = 45) | Blank control (n = 45) | In the morning of surgery day |
Matsutani (1998) | Japan | 33a (24/4) | 64 ± 7 | Methylprednisolone (10 mg/kg, n = 14) | Saline (n = 19) | At the time of anesthesia induction |
Sato (2002) | Japan | 66 (60/6) | Intervention group: 62 ± 8 Control group: 64 ± 7 | Methylprednisolone (10 mg/kg, n = 33) | Saline (n = 33) | 30 minutes before surgery |
Takeda (1997) | Japan | 30 (27/3) | Intervention group: 63 ± 7 Control group: 63 ± 10 | Methylprednisolone (10 mg/kg, n = 15) | Saline (n = 15) | Before anesthesia induction |
Takeda (2003) | Japan | 17 (15/2) | Intervention group: 65 ± 1 Control group: 60 ± 3 | Methylprednisolone (10 mg/kg, n = 7) | Saline (n = 10) | Before anesthesia induction |
Yano (2005) | Japan | 40 (36/4) | Intervention group: 64 ± 6 Control group: 56 ± 7 | Methylprednisolone (500 mg, n = 20) | Saline (n = 20) | Within 2 h before surgery |
Xu (2021) | China | 128 (69/59) | Intervention group: 62.36 ± 3.04 Control group: 62.85 ± 3.15 | Methylprednisolone sodium succinate (80 mg, n = 64) | Blank control (n = 64) | within 24 hours after surgery |
Cao (2021) | China | 44 (39/5) | Intervention group: 62.86 ± 5.22 Control group: 63.00 ± 6.19 | Methylprednisolone (500 mg, n = 22) | Saline (n = 22) | before anesthesia induction |