Variables | Vp3 (N = 22) n (%) | Vp4 (N = 18) n (%) | p value |
---|---|---|---|
Radiological outcomes | |||
Radiological assessment of main tumor, per mRECIST criteria | 0.165 | ||
CR | 4(18.2) | 2(11.1) | |
PR | 18(81.8) | 13(72.2) | |
SD | 0(0.0) | 3(16.7) | |
Radiological PVTT downstage, yes | 8(36.4) | 7(38.9) | 0.870 |
Pathological outcomes | |||
Overall pathological pCR response, yes | 6(27.3) | 4(22.2) | 0.040 |
PVTT pathological pCR response, yes | 14(63.6) | 11(61.1) | 0.870 |
R0 resection, yes | 22(100.0) | 17(94.4) | 0.450 |
Recurrence outcomes | |||
Recurrence patterns | 0.131 | ||
Intrahepatic recurrence | 7(31.8) | 10(55.6) | |
Extrahepatic metastasis | 5(22.7) | 1(5.6) | |
Synchronous intrahepatic and extrahepatic recurrences | 1(4.5) | 0(0.0) | |
Recurrence treatment | 0.444 | ||
Curative resection | 2(9.1) | 4(22.2) | |
Radiofrequency ablation | 3(13.6) | 2(11.1) | |
After-line drug therapy | 3(13.6) | 0(0.0) | |
Best support treatment | 1(4.5) | 1(5.6) | |
TACE + After-line drug therapy | 4(18.2) | 4(22.2) |