Skip to main content

Table 2 Outcomes of PVTT patients

From: Long-term survival and portal vein patency with novel PVTT surgery approach in advanced HCC patients with Vp3/4 PVTT following combination therapy of TKIs and PD-1 inhibitors

Variables

Vp3 (N = 22) n (%)

Vp4 (N = 18) n (%)

p value

Radiological outcomes

 Radiological assessment of main tumor, per mRECIST criteria

  

0.165

 CR

4(18.2)

2(11.1)

 

 PR

18(81.8)

13(72.2)

 

 SD

0(0.0)

3(16.7)

 

 Radiological PVTT downstage, yes

8(36.4)

7(38.9)

0.870

Pathological outcomes

 Overall pathological pCR response, yes

6(27.3)

4(22.2)

0.040

 PVTT pathological pCR response, yes

14(63.6)

11(61.1)

0.870

 R0 resection, yes

22(100.0)

17(94.4)

0.450

Recurrence outcomes

 Recurrence patterns

  

0.131

 Intrahepatic recurrence

7(31.8)

10(55.6)

 

 Extrahepatic metastasis

5(22.7)

1(5.6)

 

 Synchronous intrahepatic and extrahepatic recurrences

1(4.5)

0(0.0)

 

Recurrence treatment

0.444

 Curative resection

2(9.1)

4(22.2)

 

 Radiofrequency ablation

3(13.6)

2(11.1)

 

 After-line drug therapy

3(13.6)

0(0.0)

 

 Best support treatment

1(4.5)

1(5.6)

 

 TACE + After-line drug therapy

4(18.2)

4(22.2)

 
  1. Vp portal vein invasion, mRECIST modified response evaluation criteria in solid tumors, CR complete response, R0 no residual tumor, TACE transcatheter arterial chemoembolization