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Table 1 Baseline and perioperative characteristics

From: Long-term survival and portal vein patency with novel PVTT surgery approach in advanced HCC patients with Vp3/4 PVTT following combination therapy of TKIs and PD-1 inhibitors

Characteristics

Vp3 (N = 22) n (%)

Vp4 (N = 18) n (%)

p value

Demographic

 Age, median (range), year

55.0 (38–67)

57.0 (31–68)

0.682

 Gender (male/female)

19 (86.4)/ 3 (13.6)

14 (77.8)/4 (22.2)

0.680

 Etiology, HBV, yes

20 (90.9)

15 (83.3)

0.822

 Anti-viral treatment, yes

13 (59.1)

10 (55.6)

0.822

 Liver cirrhosis, yes

20 (90.9)

15 (83.3)

0.642

Baseline data

 Child–Pugh score (5/6)

13 (59.1)/ 9 (40.9)

14 (77.8)/ 4 (22.2)

0.209

 ECOG performance status = 0, yes

22 (100.0)

17 (94.4)

0.450

 Hemoglobin, median (range), g/L

137.5 (114–171)

145 (105–189)

0.189

 WBC count × 109/L, median (range)

5.62 (2.29–10.45)

5.75 (3.67–11.99)

0.276

 Platelet count × 109/L, median (range)

142 (67–327)

161 (79–312)

0.779

 AFP at baseline > 400 ng/ml, yes

10 (45.5)

11 (61.1)

0.726

 Tumor number (single/ multiple)

14 (63.6)/ 8 (36.4)

9 (50.0)/ 9 (50.0)

0.385

 Tumor diameter > 10 cm, yes

12 (54.5)

12 (66.7)

0.436

 Lymphatic metastasis, yes

4 (18.2)

7 (38.9)

0.173

Perioperative data

 AFP before surgery > 400 ng/ml, yes

2 (9.1)

6 (33.3)

0.110

 Laparotomy operation

19 (86.4)

18 (100)

0.238

 Treatment cycle, median (range), time

4.5 (3–23)

5 (3–9)

0.946

 Types of hepatectomy (left/right/segmental)

5 (22.7)/6 (27.3)/11 (50.0)

4 (22.2)/8 (44.4)/6 (33.3)

0.465

 Hospital stay after surgery, median (range), day

8.5 (5–33)

9.5 (5–20)

0.697

 Surgical time, median (range), min

265.5 (178–390)

260 (180–405)

0.697

 Blood loss, median (range), mL

375 (50–1000)

575 (50–3000)

0.058

 Child–Pugh 5th days after surgery (5/6)

15 (68.2)/7 (31.8)

14 (77.8)/4 (22.2)

0.377

  1. PVTT portal vein tumor thrombosis, Vp portal vein invasion, HBV hepatitis B virus, ECOG eastern cooperative oncology group, WBC white blood cell, AFP alpha-fetoprotein