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Table 1 General characteristics of the articles included in the meta-analysis

From: Efficacy of prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review meta-analysis

Author (year)

Centre (country)

Study type

Age

(NPWT:

control)

BMI

(NPWT:

control)

Sample size (NPWT, n)

Follow-up duration

Details of NPWT

Details of control

Mesh position

Mesh type

Outcomes

Bueno-Lledó et al. (2020) [11]

Single center (Spain)

RCT

51.6:51.3

NR

146

(NPWT, 72)

30 days

PICO, −80 mmHg× 7 days

Standard

dressing

Sublay

Synthetic

1) 2) 3) 4) 5)

Conde´-Green et al. (2013) [12]

Single center (USA)

Retrospective

54:55

36.4:36.1

56

(NPWT, 23)

15 months

VAC, −125 mmHg × 5 days

Conventional dry gauze dressing

NR

Biological

1) 3) 4) 5) 6) 7)

de Vries et al. (2017) [13]

Single center (The Netherlands)

Retrospective

58.9:59.7

26.9:27.7

66

(NPWT, 32)

30 days

PREVENA or a home-made wound dressing + VAC set, −100 mmHg × 5 days or longer

Standard dressing

Sublay, intraperitoneal

Synthetic or biological

1) 3) 4) 5) 6)

Deldar et al. (2022) [14]

Single center (USA)

Retrospective

55.0:52.9

36.4:36.2

114

(NPWT, 57)

6.64 months

VAC or PREVENA for 5–7 days

Standard dressing

Onlay, sublay, intraperitoneal

Synthetic, biological or composition

1) 2) 3) 4) 5) 7)

Diaconu et al. (2020) [15]

Single center (USA)

Retrospective

58.0:50.0

41.0:40.0

104

(NPWT, 62)

190 days

PREVENA, −125 mmHg × 5 days

Standard dressing

Onlay, inlay, sublay

No mesh, biological or synthetic

1) 2) 3) 4) 5) 6) 7)

Gassman et al. (2013) [16]

Multicenter (USA)

Retrospective

NR

NR

61

(NPWT, 29)

167 days

VAC, −125 mmHg × 7 days

Standard dressing

Intraperitoneal

Biological

1) 3) 4) 6) 7)

Hopkins et al. (2020) [17]

Single center (Canada)

Retrospective

61.0:59.0

31:31

114

(NPWT, 41)

180 days

PREVENA, −125 mmHg × 5–7 days

Standard dressing

Intraperitoneal, extraperitoneal, onlay

Synthetic, biological, composition

1) 2) 3) 4) 5) 7)

Leuchter et al. (2021) [18]

Single center (Germany)

Retrospective

56.6:63.1

31.3:30.6

108

(NPWT, 54)

38.5

months

PREVENA, −125 mmHg × 7 days

Standard dressing

Sublay

NR

1) 2) 3) 4) 5) 6) 7)

Licari et al. (2020) [19]

Single center (Italy)

Retrospective

73.3:75

28.0:26.0

180

(NPWT, 70)

90 days

PREVENA, −125 mmHg × 7 days

Standard dressing

Sublay, intraperitoneal

Synthetic

1) 2) 3) 5)

Mondal et al. (2022) [20]

Single center (India)

RCT

47.0:43.0

23.9:23.8

64

(NPWT, 30)

4 weeks

Home-made wound dressing, −125 mmHg × 5 days

Gauze dressing

Onlay

Synthetic

1) 3)

Olona et al. (2014) [21]

Single center (Spain)

Retrospective

71.0:62.0

28.1:30.08

42

(NPWT, 5)

NR

PREVENA, −125 mmHg × 7 days

Standard dressing

Onlay

Synthetic

1) 3) 4)

Pauli et al. (2013) [22]

Single center (USA)

Retrospective

56.3:55.4

33.5:34.8

119

(NPWT, 49)

30 days

Home-made wound dressing, −75 mmHg × 5 days or discharge

Sterile dry gauze adhesive dressing

Sublay

Synthetic or biological

1)

Seaman et al. (2021) [23]

Single center (USA)

Retrospective

58.0:56.0

33.0:32.0

258

(NPWT, 159)

30 days

NR

Standard dressing

NR

NR

1) 2) 3) 4) 5) 6) 7)

Soares et al. (2015) [24]

Single center (USA)

Retrospective

56.0:56.0

33.5:32.3

199

(NPWT, 115)

9 months

Home-made wound dressing, −125 mmHg × 3 days

Standard dressing

Onlay, preperitoneal, onlay, preperitoneal

Synthetic and biological

1) 2) 3) 5) 7)

Wang et al. (2021) [25]

Single center (Australia)

Retrospective

58.0:65.0

36.4:39.2

35

(NPWT, 23)

NR

PREVENA, −125 mmHg × 7 days

Standard dressing

Sublay

Biological, composite, or polypropylene

1) 3) 5)

  1. Remark: NR: not reported, outcomes: 1) SSI; 2) SSO; 3) seroma; 4) wound hematoma; 5) wound dehiscence; 6) skin necrosis; 7) hernia recurrence