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Table 2 Univariate and multivariate analyses of each factor’s ability in predicting conversion

From: A nomogram to predict conversion of laparoscopic surgery to laparotomy for Choledocholithiasis

Characteristic

Univariable analysis

Multivariable analysis

OR (95% CI)

P value

OR (95% CI)

P value

Age [year]

 

0.276

 

 ≤ 60

Ref

   

 60 ~ 80

1.175(0.745–1.851)

   

 >80

1.962(0.850–4.529)

   

Sex

 

0.040*

0.128

 Male

Ref

   

 Female

1.566(1.021–2.401)

   

BMI [Kg/m2]

 

0.551

 

  < 24

Ref

   

 24 ~ 28

1.014(0.638–1.611)

   

  > 28

0.270(0.063–1.149)

   

Diabetes (Yes/No)

0.789(0.411–1.514)

0.476

 

Hypertension (Yes/No)

0.758(0.468–1.230)

0.262

 

PUAS (Yes/No)

2.314(1.409–3.799)

0.001*

4.014(2.077–7.755)

< 0.001*

History of ERCP surgery (Yes/No)

1.310(0.519–3.302)

0.567

 

Pancreatitis (Yes/No)

0.306(0.072–1.299)

0.108

  

WBC[*109/L]

 

0.739

 

  ≤ 10

Ref

   

  > 10

1.125(0.563–2.246)

   

ALB [g/L]

 

0.018*

0.477

  ≤ 35

Ref

   

  > 35

0.578(0.367–0.910)

   

TBIL [μmol/L]

 

0.267

 

  ≤ 17.1

Ref

   

  > 17.1

0.786(0.513–1.203)

   

ALP [U/L]

 

0.921

 

  ≤ 125

Ref

   

  > 125

1.024(0.645–1.625)

   

ALT [U/L]

 

0.922

 

  ≤ 40

Ref

   

  > 40

1.024(0.639–1.640)

   

AST [U/L]

 

0.769

 

  ≤ 40

Ref

   

  > 40

1.069(0.685–1.667)

   

GGT [U/L]

 

> 0.95

 

  ≤ 50

Ref

   

  > 50

0.998(0.564–1.766)

   

Maximum diameter of CBD stone [mm]

 

< 0.001*

 

0.003*

  < 12

Ref

 

Ref

 

  ≥ 12

2.635(1.705–4.073)

 

2.312(1.318–4.057)

 

CBD stone’s location

    

 Duodenal upper segment (Yes/No)

1.612(0.989–2.627)

0.055

 

 Duodenal posterior segment (Yes/No)

1.044(0.673–1.618)

0.848

 

 Pancreatic segment (Yes/No)

0.873(0.543–1.402)

0.573

 

 Medial wall of the duodenum (Yes/No)

4.588(2.406–8.748)

< 0.001*

5.393(2.513–11.574)

< 0.001*

The number of stones in CBD

 

0.711

 

 Negative/sludge

Ref

   

 Single

0.911(0.296–2.803)

   

 Multiple

1.096(0.361–3.330)

   

IHD stone (Yes/No)

1.991(1.220–3.249)

0.006*

0.182

Thickening of gallbladder wall (Yes/No)

2.316(1505–3.564)

< 0.001*

4.318(2.454–7.597)

< 0.001*

Thickening of CBD wall (Yes/No)

6.037(3.195–11.411)

< 0.001*

4.513(2.111–9.646)

< 0.001*

Diameter of CBD

1.055(1.019–1.093)

0.002*

0.153

Stone size/CBD size

 

< 0.001*

 

0.026*

  < 0.75

Ref

 

Ref

 

  ≥ 0.75

2.650(1.666–4.216)

 

1.909(1.078–3.378)

 

Surgery method

    

 Simultaneous LC (Yes/No)

0.689(0.389–1.221)

0.202

 

 Simultaneous LH (Yes/No)

4.521(2.624–7.789)

< 0.001*

7.032(3.683–13.426)

< 0.001*

 Laser lithotripsy (Yes/No)

2.536(0.749–8.586)

0.135

  
  1. BMI body mass index, PUAS previous upper abdominal surgery, ERCP endoscopic retrograde cholangiopancreatography, WBC white blood cell, ALB albumin total bilirubin, TBIL total bilirubin, ALP alkaline phosphatase, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyl transpeptidase, CBD common bile duct, IHD intrahepatic bile duct, LC laparoscopic cholecystectomy, LH laparoscopic hepatectomy, OR odds ratio, CI confidence interval
  2. * P value < 0.05