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Table 2 Clinical data in three groups stratified by serum calcium trajectories

From: Analysis of serum calcium change trajectories and prognostic factors in patients with acute type A aortic dissection

Variables

Total (n = 383)

High group (n = 85)

Medium group (n = 259)

Continuous low group (n = 39)

P -value

Age(years), mean (SD)

49.1 ± 8.0

48.7 ± 7.8

49.1 ± 7.9

49.4 ± 9.1

0.862

Female, n, (%)

62(16.2)

11(12.9)

44(17.0)

7(17.9)

0.647

BMI (kg/m2), mean (SD)

24.7 ± 3.4

24.6 ± 3.4

24.6 ± 3.3

26.1 ± 3.3

0.033

Smoking, n, (%)

184(48.0)

47(55.3)

122(66.3)

15(38.5)

0.190

Drinking, n, (%)

123(32.1)

23(27.1)

85(32.8)

18(46.2)

0.110

Medical history

 Diabetes mellitus, n, (%)

41(10.7)

12(14.1)

24(9.3)

5(12.8)

0.411

 Hypertension, n, (%)

329(85.9)

73(81.2)

224(86.5)

36(92.3)

0.227

Prior resuscitation, n, (%)

  ≥ 3 organs, n, (%)

9(2.3)

2(2.4)

4(1.5)

3(7.7)

0.061

Echocardiography results

 LVEF (%), mean (SD)

62.34 ± 7.75

62.88 ± 7.55

62.82 ± 7.34

57.96 ± 9.50

0.001

Laboratory results

 Hb(g/L), mean (SD)

125.58 ± 18.33

128.55 ± 20.25

125.48 ± 19.11

119.76 ± 17.75

0.875

 CRP (mmol/L), median (IQR)

13.6(5.2, 32.0)

16.0(6.7, 28.8)

12.0(5.2, 34.2)

12.0(4.5, 36.0)

0.648a

 Cr(mmol/L), median (IQR)

90(73, 132)

92(70, 134)

89(73, 132)

93(77, 131)

0.670a

 BNP (mmol/L), median (IQR)

328(128, 934)

328(135, 858)

326(117, 986)

365(128, 920)

0.983a

 Serum albumin(g/l), median (IQR)

43(38,49)

38(36,53)

43(39,51)

43(37,51)

0.958a

 Serum potassium(mmol/l), mean (SD)

4.17 ± 0.56

4.06 ± 0.48

4.21 ± 0.59

4.13 ± 0.45

0.083

 Serum sodium(mmol/l), mean (SD)

136.39 ± 5.87

136.28 ± 6.12

136.51 ± 6.00

135.82 ± 4.29

0.782

 Serum chloride(mmol/l), mean (SD)

98.14 ± 7.23

98.82 ± 11.80

98.33 ± 5.20

95.43 ± 5.08

0.040

Surgical management

 Root replacement, n, (%)

14(3.7)

3(3.5)

8(3.1)

3(7.7)

0.395

 Additional CABG, n, (%)

9(2.3)

3(3.5)

5(1.9)

1(2.6)

0.481b

 Operation time(min), median (IQR)

305(265, 361)

300(265, 387)

305(270, 353)

319(262, 355)

0.955a

 CPB time(min), median (IQR)

151(132, 189)

152(133, 203)

153(130, 188)

147(134, 185)

0.791a

 Calcium infusion(g), median (IQR)

72(55, 100)

78(54, 104)

72(55, 97)

67(49, 127)

0.849a

 Calcium infusion initiated in OR, n, (%)

48(12.5)

9(10.6)

31(12.0)

8(20.5)

0.268

 Lactic acidmax (mmol/l), median (IQR)

3.7(2.3, 6.6)

4.1(2.7, 8.2)

3.5(2.0, 6.4)

4.5(3.2, 7.0)

0.003a

 VISmax

9.4(2.9, 20.0)

8.6(3.0, 20.0)

9.0(2.8, 20.0)

13.3(4.4, 20.0)

0.344a

  1. BMI body mass index, LVEF,left ventricular ejection fraction, HB hemoglobin, CRP C-reactive protein; Cr,creatinine, BNP B-type natriuretic peptide, CABG coronary artery bypass graft, CBP cardiopulmonary bypass, OR operating room, VIS vasoactive inotropic score
  2. aKruskal-Wallis H; bFisher's exact test