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Table 2 Predictors of 5-year survival of patients with HCC based on univariate analysis

From: Effect of ABO blood group on postoperative overall survival and recurrence-free survival rate in patients with hepatocellular carcinoma after hepatectomy: a multi-center retrospective cohort study

Demographic characteristics

Five-year survival rate

HR (95% CI)

P value

Age (year)

 • < 45

21.2%

Ref

-

 • 45–65

30.7%

0.66 (0.59,0.73)

0.001

 • > 65

21.4%

0.99 (0.55, 2.84)

0.81

BMI (Kg/m2)

 • ≤ 18

18.4%

Ref

-

 • 18–25

29.8%

0.71 (0.60,0.83)

0.001

 • > 25

23.2%

0.96 (0.71, 1.15)

0.087

Sex

  

0.25

 • Male

24.9%

-

 

 • Female

26.9%

  

Marital status

  

0.54

 • Unmarried

27.2%

-

 

 • Married

25.2%

  

Smoking status

  

0.61

 • Yes

24.8%

-

 

 • NO

26.1%

  

Education

   

 • Illiterate

25.3%

-

0.81

 • < Diploma

24.2%

  

 • >  = Diploma

26.1%

  

Family history of GC

  

0.12

 • No

27.2%

  

 • Yes

25.2%

  

Alcohol consumption

  

0.44

 • No

26.6

  

 • Yes

24.8

  

 • Unknown & missing

25.4

  

Child–Pugh stage

  

0.12

 • A

28.1

-

 

 • B

24.7

  

 • Unknown & missing

26.2

  

Tumor size (cm)

 • ≤ 5

32.5%

Ref

-

 • > 5

18.9%

1.73 (1.12,2.25)

0.001

 • Unknown & missing

21.1%

1.48 (0.99,2.11)

0.074

Metastasis

 • No

31.6%

Ref

-

 • Yes

21.2%

1.52 (1.11, 1.93)

0.001

 • Unknown & missing

23.8%

1.32 (1.06,1.6)

0.004

Involved Lymph node

 • < 2

32.9%

Ref

-

 • ≥ 2

20.11%

1.65 (1.16,2.17)

0.001

 • Unknown & missing

24.6%

1.31 (1.04,1.62)

0.026

Differentiation grade

 • Well

33.2%

Ref

-

 • Moderate

24.3%

1.36 (1.08,1.65)

0.006

 • Poor

17.2%

1.94 (1.44,2.46)

0.0001

 • Unknown & missing

25.1%

1.30 (1.01,1.62)

0.043

Serum AFP level

 • < 400 ng/ml

30.1%

Ref

-

 • ≥ 400 ng/ml

20.4%

1.51 (1.12, 1.93)

0.0001

 • Unknown & missing

25.6%

1.17 (0.96,1.43)

0.098

Cirrhosis

  

0.24

 • Yes

26.6%

-

 

 • No

24.7%

  

 • Unknown & missing

25.3%

  

ABO Blood Type

 • O

31.1%

Ref

-

 • A

12.9%

2.41 (1.66,3.17)

0.001

 • B

24.1%

1.29 (1.02,1.56)

0.045

 • AB

29.2%

1.06 (0.86, 1.121)

0.18

ABO Blood Type

  

0.001

 • Non-A

29.7%

Ref

 

 • A

12.9%

2.3 (1.46,3.15)

 

Hepatitis type

 • None

28.3%

Ref

-

 • HBV

20.14%

1.41 (1.02,1.81)

0.008

 • HCV

25.1%

1.13 (0.97, 1.3)

0.084

 • HBV + HCV

19.1%

1.42 (0.98,1.89)

0.092

 • Unknown & missing

22.4%

1.25 (0.92, 1.59)

0.11

Hepatitis type

  

0.013

 • Non-HBV

26.3%

Ref

 

 • HBV

20.14%

1.29 (1.04,1.55)

 

RH

 

-

0.88

 • + 

25.8%

  

 • -

25.3%

  
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