Table 3 Univariate and multivariate logistic regression analyses for predicting postoperative major morbidity after partial hepatectomy for hepatocellular carcinoma after PSM.

Age

Elderly vs. Nonelderly

0.78(0.58–1.06)

0.118

Sex

male vs. female

1.1(0.74–1.64)

0.642

ASA score

> 2 vs. ≤ 2

0.56 (0.39–0.8)

0.001

1.01 (0.53–1.87)

0.966

Overweight

Yes vs. No

0.84 (0.6–1.19)

0.331

Comorbidity

Yes vs. No

0.85 (0.61–1.18)

0.331

Preoperative AFP level

> 400 ug/L vs.≤ 400 ug/L

1.91 (1.35–2.7)

< 0.001

0.48 (0.23–0.93)

0.037

Preoperative ALT level

> 40 U/L vs. ≤ 40 U/L

0.92 (0.66–1.27)

0.610

Preoperative AST level

> 40 U/L vs. ≤ 40 U/L

1.45 (1.07–1.98)

0.018

0.96 (0.54–1.68)

0.889

HBV infection

Yes vs. No

1.19 (0.77–1.83)

0.441

Cirrhosis

Yes vs. No

1.3 (0.95–1.77)

0.096

0.75 (0.4–1.38)

0.358

Portal hypertension

Yes vs. No

1.18 (0.85–1.64)

0.324

Child‒Pugh grade

B vs. A

3.51 (1.35–9.17)

0.01

2.33 (1.38–5.89)

0.044

BCLC staging

B/C vs. A

2.22 (1.59–3.11)

< 0.001

1.22 (0.78–1.86)

0.472

Open hepatectomy

Yes vs. No

0.39 (0.26–0.6)

< 0.001

1.02 (0.45–2.14)

0.964

Margin width

< 1 cm vs. ≥ 1 cm

1.27 (0.83–1.94)

0.280

Blood loss

> 600ml vs. ≤ 600ml

2.27 (1.28–4.02)

0.050

1.19 (0.4–3.11)

0.742

Intraoperative blood transfusion

Yes vs. No

1.54 (1.08–2.2)

0.016

0.37 (0.16–0.79)

0.013

Operation duration

> 180 min vs. ≤ 180 min

1.24 (0.89–1.73)

0.200

Anatomical hepatectomy

Yes vs. No

1.25 (0.92–1.7)

0.152

Extended hemihepatectomy

Yes vs. No

1.64 (1.09–2.45)

0.017

7.46 (4.03–14.07)

0.022

Occlusion

Yes vs. No

1.28 (0.94–1.75)

0.119

Macrovascular invasion

Yes vs. No

1.88 (1-3.53)

0.051

1.36 (0.43–3.82)

0.580

MVI

Yes vs. No

1.60 (1.14–2.24)

0.006

1.46 (0.78–2.67)

0.230

Satellite nodules

Yes vs. No

1.92(1.14–3.24)

0.015

0.96 (0.36–2.29)

0.927

Poor Tumor differentiation

Yes vs. No

0.83 (0.58–1.19)

0.310

Incomplete tumor envelope

Yes vs. No

2.28 (1.32–3.94)

0.003

0.66 (0.22–1.71)

0.421

Tumor diameter

>5cmvs. ≤ 5 cm

1.99 (1.46–2.72)

< 0.001

1.49 (1.08–2.82)

0.022