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Table 3 Univariate and multivariate analyses of baseline variables for 30-day mortality prediction in the training cohort

From: Machine learning-based nomogram for 30-day mortality prediction for patients with unresectable malignant biliary obstruction after ERCP with metal stent: a retrospective observational cohort study

Variants

Univariate analyses

Multivariate analyses

OR (95%CI)

p

OR (95%CI)

p

Male

2.2 (0.84–5.80)

0.11

  

Age

1 (0.97–1.10)

0.72

  

High obstruction

2.5 (0.99–6.30)

0.052

  

Two-stent placements

0.87 (0.11–7.10)

0.9

  

Lymph node metastasis

3.1 (1.2–7.9)

0.016

2.29 (0.59–8,98)

0.233

Distant metastasis

4.9 (1.9–12.0)

 < 0.001

7.96 (1.44–44.10)

0.018

Cholangitis before stent insertion

0.93 (0.3–2.9)

0.9

  

Post-ERCP complications

4.8 (2–12)

 < 0.001

6.03 (1.52–24.01)

0.011

Child–Pugh class C

3.3 (1.1–10.0)

0.032

1.14 (0.16–8.11)

0.894

Pancreatic Cancer

1

   

Gallbladder cancer

2 (0.49–8.10)

0.33

0.33 (0.03–3.40)

0.349

Cholangiocarcinoma

1.7 (0.6–5.0)

0.31

0.60 (0.13–2.71)

0.504

Ampullary cancer

0.6 (0.072–5.100)

0.64

1.06 (0.09–12.88)

0.966

Other

5 (1.3–19.0)

0.019

0.79 (0.10–5.99)

0.822

Ascites

2.6 (1.1–6.3)

0.029

1.25 (0.34–4.55)

0.738

White blood cell count (109/L)

1.1 (1.0–1.2)

0.027

1.04 (0.93–1.16)

0.529

Red blood cell count (1012/L)

0.55 (0.27–1.10)

0.099

  

Hemoglobin (g/L)

0.98 (0.95–1.00)

0.089

  

Platelet (109/L)

1 (0.99–1.00)

0.35

  

TB (mg/dl)

1 (1–1)

 < 0.001

1.01 (1.00–1.01)

0.009

ALT (u/L)

0.99 (0.98–1.00)

0.049

1.00 (0.99–1.01)

0.661

AST (u/L)

1 (0.99–1.00)

0.87

  

Albumin (g/L)

0.88 (0.81–0.96)

0.004

0.90 (0.78–1.03)

0.131

Creatinine (μmoI/L)

1 (1–1)

0.15

  

PT (s)

1.2 (1.0–1.4)

0.044

1.04 (0.87–1.24)

0.676

Successful drainagea

0.11 (0.032–0.380)

 < 0.001

0.12 (0.03–0.54)

0.005

  1. ERCP Endoscopic retrograde cholangiopancreatography, TB Total bilirubin, ALT alanine aminotransferase, AST Aspartate aminotransferase, PT Prothrombin time, OR Odds ratio, CI Confidence interval
  2. Statistically significant with p < 0.05
  3. aDefined by a decrease in TB of > 30% within 1 week after surgery or a decrease in TB close to the normal level (TB \(\le\) 17.1umol/l) in the later period