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Table 5 Cox proportional-hazards models of HSS after PSM

From: Breast conservation therapy decreased heart-specific mortality in breast cancer patients compared with mastectomy

Variables

Univariable analysis

Multivariable analysis

HR

95%CI

P value

HR

95%CI

P value

Age at diagnosis (year)

      

≤50

Ref

  

Ref

  

>50

4.786

3.921–5.843

<0.0001

4.001

3.26–4.91

<0.0001

Race

      

White

Ref

  

Ref

  

Black

1.968

1.632–2.372

<0.0001

1.855

1.531–2.248

<0.0001

Othersa

0.709

0.519–0.969

0.031

0.86

0.629–1.176

0.345

Unknown

0

0-1.32E + 57

0.9

0

0-5.09E + 41

0.876

AJCC Stage

      

I

Ref

  

Ref

  

II

1.637

1.055–2.542

0.028

1.548

0.997–2.405

0.052

III

2.657

1.704–4.144

<0.0001

2.125

1.361–3.318

0.001

ER status

      

Negative

Ref

  

Ref

  

Positive

0.753

0.64–0.885

0.001

0.914

0.73–1.144

0.431

PR status

      

Negative

Ref

  

Ref

  

Positive

0.663

0.568–0.772

<0.0001

0.759

0.614–0.938

0.31

Marital status

      

Married

Ref

  

Ref

  

Widowed

5.442

4.438–6.672

<0.0001

3.326

2.702–4.095

<0.0001

Othersb

1.668

1.395–1.994

<0.0001

1.505

1.254–1.806

<0.0001

Unknown

1.611

1.024–2.534

0.039

1.467

0.932–2.309

0.098

Laterality

      

Left

Ref

  

Ref

  

Right

0.941

0.807–1.096

0.433

0.941

0.817–1.099

0.441

Type of surgery

      

BCT

Ref

  

Ref

  

Mastectomy

1.367

1.173–1.594

<0.0001

1.311

1.125–1.529

0.001

  1. a, other includes Latinos, Alaskan native, Asian, American Indian and Pacific Islander. b, others includes divorced, single and unmarried