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Table 3 Cox proportional-hazards models of HSS

From: Breast conservation therapy decreased heart-specific mortality in breast cancer patients compared with mastectomy

Variables

Univariable analysis

multivariable analysis

HR

95%CI

P value

HR

95%CI

P value

Age at diagnosis (year)

      

≤50

Ref

  

Ref

  

>50

4.972

4.305–5.742

<0.0001

4.423

3.818–5.123

<0.0001

Race

      

White

Ref

  

Ref

  

Black

1.74

1.525–1.987

<0.0001

1.647

1.438–1.886

<0.0001

Othersa

0.68

0.548–0.842

<0.0001

0.771

0.622–0.956

0.018

Unknown

0

0-1.45E + 33

0.836

0

0-3.02E + 37

0.852

AJCC Stage

      

I

Ref

  

Ref

  

II

1.444

1.254–1.663

<0.0001

1.348

1.166–1.557

<0.0001

III

2.467

2.132–2.855

<0.0001

1.935

1.63–2.297

<0.0001

ER status

      

Negative

Ref

  

Ref

  

Positive

0.806

0.724–0.898

<0.0001

0.892

0.766–1.038

0.138

PR status

      

Negative

Ref

  

Ref

  

Positive

0.742

0.67–0.822

<0.0001

0.874

0.758–1.009

0.066

Marital status

      

Married

Ref

  

Ref

  

Widowed

5.408

4.737–6.175

<0.0001

3.377

2.95–3.866

<0.0001

Othersb

1.525

1.352–1.721

<0.0001

1.45

1.283–1.64

<0.0001

Unknown

1.662

1.237–2.234

0.001

1.533

1.14–2.061

0.005

Laterality

      

Left

Ref

  

Ref

  

Right

0.976

0.881–1.08

0.634

0.977

0.883–1.082

0.659

Type of surgery

      

BCT

Ref

  

Ref

  

Mastectomy

1.703

1.535–1.888

<0.0001

1.364

1.204–1.545

<0.0001

  1. a, other includes Latinos, Alaskan native, Asian, American Indian and Pacific Islander. b, others includes divorced, single and unmarried
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