Table 4 Statistical evaluation of blood’s peripheral cellular groups
Cells population compared | Group A | Group B | Group C | P value | |
|---|---|---|---|---|---|
%MN | 1.3 (1–1.6) | 2.7 (2.1–3.4) | 0.7 (0.4–1.3) | B vs. C p = 0.002 A vs. C p = 0.07 | |
B cell populations % B cells CD19+ | 10.5 (7.4–14.4) | 10.3 (5.85–12.4) | 8.4 (6.7–9.7) | B vs. C p = 0.4 A vs. C p = 0.1 | |
% B cells naive CD19 + CD27-IgD+ | 58 (53.5–62.6) | 64.5 (58–70.9) | 54.6 (46.2–59.2) | B vs. C p = 0.01 A vs. C p = 0.4 | |
Class-switched memory CD19 + IgD-IgM- CD38-CD27+ | 15 (11.1–20.6) | 12.8 (10.5–14) | 54.6 (46.2–59.2) | B vs. C p = 0.001 A vs. C p = 0.06 | |
% B cells Class-unswitched memory CD19 + IgD + IgM + CD38-CD27+ | 18.7 (14.5–23.3) | 15.4 (11.8–18.5) | 22.6 (20.1–25.8) | B vs. C p = 0.002 A vs. C p = 0.05 | |
Tcell population% | |||||
T cells CD3+ | 62(53.5–75.1) | 75.3(56.3–79.6) | 76.8(60.1–82.1) | B vs. C p = 0.6 A vs. C p = 0.4 | |
% T cells CD4+ | 62.7(59.9–67.2) | 61.8(53.4–67.2) | 57.5(55–65) | B vs. C p = 0.6 A vs. C p = 0.4 | |
% T cells CD8+ | 30(24–31.6) | 30.7(24.6–35.3) | 32.1(28.6–35) | B vs. C p = 0.5 A vs. C p = 0.1 | |
% T cells CD4 + PD1+ | 20.5(13.1–29.7) | 29.7(26.7–30.5) | 23.5(13.1–25.6) | B vs. C p = 0.05 A vs. C p = 0.8 | |
% Naive-T cells CD4 + CCR7 + CD45RA+ | 26.9(20.6–37.4) | 37.1(31.6–48.2) | 27.3 (24–39.4) | B vs. C p = 0.4 A vs. C p = 0.6 | |
% effector memory T cells CD4 + CCR7 − CD45RA− | 22.7 (14.5–29.3) | 15.8(11.1–25.7) | 22.2(14.9–24.7) | B vs. C p = 0.1 A vs. C p = 0.7 | |
% central memory T cells CD4 + CCR7 + CD45RA- | 48.6 (42.5–55.8) | 42(34.1–43.2) | 46.5(40.1–58.2) |