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Table 3 Univariate and multivariate cox regression comparing patients with paraaortic lymph node metastasis (PALN+), no paraaortic lymph node metastasis (PALN-) and patients undergoing surgical exploration only (EXP).

From: Impact of para aortic lymph node removal on survival following resection for pancreatic adenocarcinoma

 

Variable

Subtype

Hazard Ratio (95% conf. interval)

p-value

Univariate

Resection type*

PALN-

0.57(0.31–1.05)

0.05

  

EXP

2.31(1.30–4.11)

< 0.001

 

Demographic

Female sex

0.80(0.67–0.97)

0.02

  

Age

1.01(1.00-1.03)

< 0.001

  

Charlson Comorbidity Index

1.06(1.01–1.10)

< 0.001

 

Oncology treatment

Preoperative chemotherapy

0.54(0.43–0.70)

< 0.001

  

Postoperative Chemotherapy

0.42(0.34–0.51)

< 0.001

Multivariate

Resection type*

PALN-

0.50(0.27–0.93)

0.03

  

EXP

2.36(1.32–4.20)

< 0.001

 

Demographic

Female sex

0.85(0.71–1.03)

0.10

  

Age

1.01(0.99–1.01)

0.39

  

Charlson Comorbidity Index

1.03(0.99–1.07)

0.17

 

Oncology treatment

Preoperative chemotherapy

0.43(0.33–0.55)

< 0.001

  

Postoperative Chemotherapy

0.39(0.32–0.49)

< 0.001

  1. *PALN- and EXP groups are compared with PALN + patients.
  2. Multivariate models were corrected for the shown covariates