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Table 2 Outcomes of the primary and secondary indicators

From: Comparison of the efficacy and safety of antibiotic treatment and appendectomy for acute uncomplicated appendicitis: a systematic review and meta-analysis

Indicators

Antibiotic group

Surgery group

RR (95% CI)

z

p

Cure rate of complication-free treatment at 1 year

69.4%(468/674)

88.8%(609/686)

0.81(0.73–0.91)

3.65

0.000 < 0.05

Total complications

3.9%(50/1270)

9.5%(119/1257)

0.43(0.31–0.58)

5.36

0.000 < 0.05

4.8%(30/631)

14.5%(91/626)a

0.34(0.23–0.49)

5.55

0.000 < 0.05

3.1%(20/639)

4.4%(28/631)b

0.72(0.41–1.24)

1.19

0.236

Complications after appendectomy

9.5%(119/1257)

11.9%(47/394)

1.38(0.70–2.73)

0.93

0.353

Therate of complicated appendicitis formed after treatments

5%(63/1264)

9.9%(128/1289)

0.71(0.36–1.42)

0.96

0.338

The rate of appendectomy with non-appendicitis

4.2%(30/721)

3.7%(27/732)

1.11(0.69–1.79)

0.43

0.670

Length of hospital stay

NA

NA

0.08(-0.11-0.27)c

0.80

0.422

Quality of life after treatments

NA

NA

0.09(-0.03-0.20)c

1.53

0.127

The effect of appendicoliths on the effectiveness of antibiotic treatment

38.1%(101/265)d

18.9%(140/740)e

2.94(1.28–6.74)

2.55

0.011 < 0.05

  1. NA Not Available
  2. aOpen surgery
  3. bLaparoscopic surgery
  4. cSMD (95%CI)
  5. dThe appendicolith rate of the patients whose symptoms were not improved in the antibiotic treatment group
  6. eThe appendicolith rate of the patients whose symptoms were improved in the antibiotic treatment group