Table 3 Univariate analyses of risk factors for anastomotic leakage
Factors | Hazard Ratio | 95% CI | p-value |
|---|---|---|---|
Age (≥ 75 vs. <75 years) | 0.602 | 0.192–1.892 | 0.385 |
Sex (Male vs. Female) | 7.885 | 1.774–35.054 | 0.007 |
ASA physical status (3 vs. 1–2) | 1.893 | 0.632–5.675 | 0.254 |
Diabetes mellitus (Absent vs. Present) | 1.462 | 0.494–4.326 | 0.492 |
Steroid use (Absent vs. Present) | N/A | ||
Smoking (Absent vs. Present) | 0.575 | 0.227–1.461 | 0.245 |
BMI (≥ 25 vs. <25 kg/m2) | 1.505 | 0.564–4.016 | 0.414 |
Tumor location (Below the peritoneal reflection vs. Above the peritoneal reflection) | 1.557 | 0.414–5.863 | 0.513 |
Tumor diameter (≥ 5 vs. <5 cm) | 2.860 | 1.116–7.328 | 0.029 |
Neoadjuvant chemoradiotherapy (Present vs. Absent) | 2.877 | 0.285–29.058 | 0.370 |
Number of stapler cartridges for rectal transection (3 vs. 1–2) | 2.145 | 0.228–20.191 | 0.505 |
Diameter of circular stapler (29 vs. 25 mm) | 1.361 | 0.536–1.361 | 0.516 |
Additional reinforcement (Absent vs. Present) | 1.214 | 0.460–3.201 | 0.696 |
Diverting ileostomy (Absent vs. Present) | 3.643 | 1.153–11.511 | 0.028 |
Intraoperative blood loss (≥ 100 vs. <100 ml) | 1.296 | 0.402–4.179 | 0.664 |
Operation time (≥ 360 vs. <360 min) | 2.792 | 1.020–7.642 | 0.046 |
Circular Stapler (Manual vs. Powered) | 3.611 | 1.018–12.810 | 0.047 |