Table 2 Patients’ characteristics in Siewert II AEG cohort

Patient-related factors

 Age (years)

75.38 ± 13.22

64.25 ± 12.31

0.0504

 Sex (male/female)

6/2

13/4

0.9360

 BMI (kg/m²)

23.63 ± 4.37

23.12 ± 3.07

0.6412

Comorbidities

 Stroke (no/yes)

6/2

15/2

0.3998

 Renal failure (no/yes)

8/0

17/0

N.S

 Liver cirrhosis (no/yes)

8/0

16/1

0.4419

 Cardiac disease (no/yes)

8/0

15/2

0.2703

 Pulmonary disease (no/yes)

8/0

17/0

N.S

 Diabetes mellitus (no/yes)

8/0

17/0

N.S

Tumor-related factors

 pT (1/2/3/4)

3/0/4/1

9/2/5/1

0.5419

 pN (0/1/2/3)

7/0/1

12/3/2

0.4451

 fStage (I/II/III)

3/4/1

10/5/2

0.5716

 Lymphatic invasion (− / +)

4/4

9/8

0.8908

 Venous invasion (− / +)

3/5

6/11

0.9146

 CEA (< 5/ ≥ 5 ng/mL)

7/1

17/0

0.6863

 CA19-9 (< 37/ ≥ 37 IU/mL)

7/1

16/1

0.5694

Treatment-related factors

 Procedure (TG/PG)

6/2

11/6

0.2105

 Reconstruction

0.4641

 Roux-en-Y esophagojejunostomy

6

11

 mSOFY

2

2

 Kamikawa flap

0

1

 Esophagogastrostomy (circular)

0

3

 Neoadjuvant chemotherapy (no/yes)

7/1

17/0

0.1368

 Adjuvant chemotherapy (no/yes)

5/3

15/2

0.1335