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Table 1 Perioperative baseline characteristics of patients with hepatocellular carcinoma in the ERAS and Non-ERAS groups

From: Enhanced recovery after surgery in primary liver cancer patients undergoing hepatectomy: experience from a large tertiary hospital in China

 

All (N = 318)

ERSA (N = 150)

Non-ERSA (N = 168)

P

Age at diagnosis (year)

55.0 (10.5)

54.2 (10.8)

55.7 (10.1)

0.210

Sex

   

0.885

Female

72 (22.6%)

35 (23.3%)

37 (22.0%)

 

Male

246 (77.4%)

115 (76.7%)

131 (78.0%)

 

BMI

23.1 [20.9;24.9]

22.7 [20.6;24.6]

23.4 [21.3;25.3]

0.149

Education level

   

0.823

No school/primary education

79 (24.8%)

37 (24.7%)

42 (25.0%)

 

Middle Education

106 (33.3%)

53 (35.3%)

53 (31.5%)

 

High education

68 (21.4%)

29 (19.3%)

39 (23.2%)

 

University education

65 (20.4%)

31 (20.7%)

34 (20.2%)

 

Comorbidity

   

0.230

No

273 (85.8%)

133 (88.7%)

140 (83.3%)

 

Yes

45 (14.2%)

17 (11.3%)

28 (16.7%)

 

Chronic smoking

   

0.748

No

239 (75.2%)

111 (74.0%)

128 (76.2%)

 

Yes

79 (24.8%)

39 (26.0%)

40 (23.8%)

 

Chronic drinking

   

0.065

No

273 (85.8%)

135 (90.0%)

138 (82.1%)

 

Yes

45 (14.2%)

15 (10.0%)

30 (17.9%)

 

ALT (U/L)

26.0 [19.0;33.0]

25.0 [19.0;33.0]

27.0 [20.0;34.0]

0.264

AST (U/L)

24.0 [17.0;30.8]

23.0 [17.0;30.0]

25.0 [18.0;31.0]

0.375

PLT (×109 L)

194 [139;240]

193 [144;233]

196 [136;247]

0.546

HB (g/L)

138 [125;151]

138 [127;150]

138 [123;151]

0.587

WB (×109 L)

5.38 [4.38;6.64]

5.20 [4.26;6.51]

5.54 [4.67;6.83]

0.087

Creatinine (umol/L)

73.5 [63.0;82.8]

73.0 [62.0;81.0]

74.0 [64.0;84.0]

0.362

ALB (g/L)

41.2 [38.7;43.6]

41.5 [38.5;44.2]

41.0 [39.1;43.2]

0.310

TBIL (umol/L)

11.8 [8.53;15.9]

11.6 [8.60;14.8]

11.9 [8.50;17.2]

0.136

ASA:

   

0.185

I + II

225 (70.8%)

112 (74.7%)

113 (67.3%)

 

III

93 (29.2%)

38 (25.3%)

55 (32.7%)

 

Surgical approach

   

0.679

Laparoscopic technique

95 (29.9%)

47 (31.3%)

48 (28.6%)

 

Open

223 (70.1%)

103 (68.7%)

120 (71.4%)

 

Extent of operation

   

0.835

Single segmentectomy

139 (43.7%)

67 (44.7%)

72 (42.9%)

 

Two combined segmentectomies

122 (38.4%)

55 (36.7%)

67 (39.9%)

 

Major hepatectomy

57 (17.9%)

28 (18.7%)

29 (17.3%)

 

Surgical time (minute)

270 [217;333]

274 [226;334]

270 [212;329]

0.287

Blood volume intraoperative (ml)

300 [100;500]

225 [100;5.00]

300 [100;500]

0.081

  1. Continuous variables are presented as mean (SD, standard deviation) or median (IQR, interquartile range); the categorical variables are presented as numbers (%)
  2. ERAS, enhanced recovery after surgery; BMI, body mass index; ALT, glutamic pyruvic transaminase; AST, glutamic oxaloacetic transaminase; PLT, platelet; HB, hemoglobin; WB; white blood cell; ALB, albumin; TBIL, total bilirubin; ASA, American Society of Anesthesiologists