Table 5 Univariate and multivariate analysis of disease-free survival

Age (years)

1.032 (1.013–1.051)

< 0.01*

1.024 (1.005–1.042)

0.012*

Sex (female/male)

0.876 (0.689–1.113)

0.277

BMI (kg/m²)

0.979 (0.945–1.014)

0.243

T2DM (yes/no)

0.997 (0.727–1.368)

0.986

Tumor site (colon/ rectum)

1.402 (1.107–1.775)

< 0.01*

1.341 (1.050–1.712)

0.019*

Tumor stage (IV/III/II/I)

2.129 (1.825–2.485)

< 0.01*

2.094 (1.788–2.452)

< 0.01*

Smoking (yes/no)

1.050 (0.825–1.338)

0.691

Drinking (yes/no)

0.968 (0.746–1.257)

0.809

Hypertension (yes/no)

0.867 (0.678–1.108)

0.253

CHD (yes/no)

1.001 (0.669–1.499)

0.995

Tumor size (≥ 5 cm/<5 cm)

1.506 (1.192–1.903)

< 0.01*

1.206 (0.950–1.531)

0.125

Bicarbonate (higher/lower)

0.723 (0.572–0.914)

< 0.01*

0.859 (0.676–1.092)

0.215

Lactate (higher/lower)

1.886 (1.219–2.919)

< 0.01*

2.020 (1.230–3.191)

< 0.01*

Overall complications (yes/no)

1.584 (1.240–2.024)

< 0.01*

1.484 (1.158–1.902)

< 0.01*