Table 4 Univariate and multivariate analysis of overall survival

Age (years)

1.042 (1.021–1.063)

< 0.01*

1.033 (1.013–1.054)

< 0.01*

Sex (female/male)

0.861 (0.730–1.015)

0.074

BMI (kg/m²)

0.974 (0.936–1.013)

0.192

T2DM (yes/no)

1.090 (0.775–1.534)

0.619

Tumor site (colon/ rectum)

1.510 (1.162–1.963)

< 0.01*

1.403 (1.069–1.840)

0.014*

Tumor stage (IV/III/II/I)

2.250 (1.896–2.671)

< 0.01*

2.202 (1.848–2.625)

< 0.01*

Smoking (yes/no)

1.061 (0.813–1.385)

0.662

Drinking (yes/no)

0.971 (0.728–1.295)

0.840

Hypertension (yes/no)

0.837 (0.637–1.099)

0.201

CHD (yes/no)

0.969 (0.939–1.957)

0.890

Tumor size (≥ 5 cm/<5 cm)

1.690 (1.303–2.192)

< 0.01*

1.327 (1.018–1.730)

0.036*

Bicarbonate (higher/lower)

0.636 (0.491–0.823)

< 0.01*

0.769 (0.590–1.002)

0.052

Lactate (higher/lower)

1.818 (1.136–2.911)

0.013*

1.981 (1.230–3.191)

< 0.01*

Overall complications (yes/no)

1.804 (1.383–2.352)

< 0.01*

1.656 (1.266–2.167)

< 0.01*