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Table 2 Characteristics and quality evaluation of the included studies

From: A meta-analysis of risk factors for non-superficial surgical site infection following spinal surgery

Author, year

Study design

Date of data collection

Samples that meet the inclusion criteria (N)

Type of operation

d-SSI or organ/space SSI

risk factors

Statistical method

NOS scores

LIM, S 2018 [2]

retrospective study

2006–2011

111

Single level lumbar fusion surgery

organ/space SSI

1. age (> 70)

2. female

3. ASA > 2

4. operative time > 6 h

Logistic regression analysis

6

Zhang, Z 2015 [14]

retrospective study

2008–2013

99

Posterior thoracic and lumbar surgery

d-SSI

1. obesity

2. diabetes mellitus

3. number of surgical levels ≥ 3

Logistic regression analysis

7

Rao, S B 2011 [15]

Prospective study

2008.01–2008.12

57

Posterior spine fusion surgery

d-SSI

1. drainage time(per/day)

2.BMI

3.male

Logistic regression analysis

7

Pennington, Z 2019 [16]

retrospective study

2012–2018

38

Spinal surgery

d-SSI

1. drainage time(per/day)

2.BMI

3.hemoglobin

Logistic regression analysis

5

Kim, J 2022 [17]

retrospective study

2012–2018

767

Instrumented spinal fusion surgery

d-SSI

1. age > 60

2.male

3.rural residence

4.multiple approaches

5.cerebrovascular disease

6.peripheral vascular disease

7.chronic pulmonary disease

8.rheumatologic disease

9.liver disease

10.diabetes mellitus

11.hemiplegia or paraplegia

12.allogenous transfusion

13.use of systemic steroids > 2 weeks

Logistic regression analysis

8

Seki, T 2013 [18]

retrospective study

2007–2012

10

Spinal surgery

d-SSI

1. operative time

2. drainage time

Logistic regression analysis

6

Kim, B D 2014 [19]

retrospective study

2006–2011

unknown

Single-level lumbar fusion surgery

organ/space SSI

1. operative time > 5 h

Logistic regression analysis

6

Miller, E M 2022 [20]

retrospective cohort study

2009–2019

unknown

Anterior lumbar interbody fusion surgery

organ/space SSI

1. BMI > 35

Logistic regression analysis

7

De la Garza-Ramos, R 2016 [21]

retrospective study

2006–2012

264

Surgery for degenerative spine disease

d-SSI or organ/space SSI

1. renal morbidity

2. hemato-oncological morbidity

3.chronic steroid use

4. diabetes mellitus

5.obesity

6. lengths of stay

7.operative time

Logistic regression analysis

6

Wang, S 2022 [22]

retrospective study

2013–2018

20

Posterior lumbar interbody fusion surgery

d-SSI

1. local use of vancomycin powder

2.BMI

3. drinking

4. urinary tract infections

5. diabetes mellitus

6. blood transfusions

7. number of surgical levels

8. postoperative drainage volume

Logistic regression analysis

8

White, SJW 2019 [23]

retrospective study

2008–2015

52

Elective anterior lumbar fusion surgery

d-SSI

1. steroid use

Logistic regression analysis

6