Table 2 Correlative effect on survival of the patient based on Univariate cox analysis

Infiltration depth

1.401

1.014–1.935

0.041

Macroscopic classification

0.543

0.304–0.972

0.040

BRAF

2.771

1.205–6.371

0.016

Vascular tumor thrombus

2.447

1.462–4.096

0.001

CA-199

1.004

1.003–1.005

< 0.001

Lymph node metastasis

4.399

2.747–7.043

< 0.001

CEA

1.003

1.002–1.004

< 0.001

 N stage

2.722

2.069–3.582

< 0.001

TNM stage

4.375

3.169–6.041

< 0.001

Number of positive lymph nodes

1.250

1.192–1.310

< 0.001

Metastasis

12.494

7.545–20.689

< 0.001

Chemotherapy

2.172

1.349–3.496

0.001