Table 3 Antibiotic Stewardship team’s interventions among SOT recipients (N = 4051)

Discontinue unnecessary antibiotics

2971

 Discontinue carbapenems

1001

 Discontinue Metronidazole

871

 Discontinue Aminoglycosides

508

 Discontinue Cephalosporins

471

 Discontinue Fluoroquinolones

88

 Discontinue polymyxin E

26

 Others

6

Start necessary antibiotics

302

 Start carbapenems according microbiological surveillance

105

 Start Antibiotic against Gram positive bacteria

101

 Start beta-lactam beta-lactamase inhibitors according microbiological surveillance

96

Deescalate broad spectrum antibiotics

221

 Switch carbapemens to beta-lactam beta-lactamase inhibitors

172

 Switch linezolide to vancomycine

22

 Switch vancomycine to anti-staphylococcal penicillins

16

 Switch polymyxin E to Continuous high-dose infusion of carbapenems

11

Optimized therapeutic dose of antibiotics

209

 Decrease total daily dose of antibiotics

177

 Increase total daily dose dose of antibiotics

32

 Adjust dose of antibiotics in renal impairment

217

 Consider drug-antibiotics interactions

54

 Change of IV route to PO form

77