Surgery-related disseminated intravascular coagulation predicts postoperative complications

BMC Surgery

Table 6 Risk factors for high CCI according to univariate and multivariate analyses

	Univariate analysis			Multivariate analysis without adjustment for DIC			Multivariate analysis with adjustment for DIC
Subject	OR	CI	P-value	OR	CI	P-value	OR	CI	P-value
Preoperative factor
Gender Male	2.98	0.63–13.98	0.16
Age, years	1.02	0.96–1.09	0.60	1.04	0.97–1.11	0.27	1.04	0.96–1.12	0.34
BMI, kg/m²	0.93	0.80–1.10	0.41
Diabetes	1.03	0.33–2.84	0.95
Biliary drainage	2.20	0.75–6.43	0.15
Cholangitis in medical history	3.05	0.47–19.74	0.24
ALBI score	9.42	0.42–210.92	0.16
AST⁺¹⁰, U/L	1.26	1.08–1.47	< 0.01	1.25	1.06–1.47	< 0.01	1.19	0.99–1.43	0.06
Operation factor
Biliary tract reconstruction	2.25	0.80–6.31	0.12
Lymph node dissection	2.33	0.81–6.74	0.12
Operation time, h	1.26	1.05–1.50	< 0.01	1.30	1.07–1.59	< 0.01	1.23	0.99–1.53	0.06
Bleeding volume ⁺¹⁰⁰, ml	1.02	0.98–1.06	0.24
Hepatectomy	0.98	0.31–3.05	0.97
Perioperative factor
DIC on day 1	9.86	3.23–30.07	< 0.01	-	-	-	6.12	1.82–20.47	< 0.01

DIC disseminated intravascular coagulation, BMI body mass index, AST aspartate transaminase

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