Table 4 Uni- and multivariate predictive factors of POPF after DP

Age (years)

  > 70

49

0.82

0.34–1.90

0.65

  < 70

73

1

Sex

 Male

71

1.32

0.58–3.18

0.51

 Female

51

1

BMI (kg/m²)

  > 24

42

2.13

0.91–5.04

0.08

2.49

0.79–8.00

0.12

  < 24

80

1

1

Albumin (g/dl)

  > 3.6

112

0.45

0.26

  < 3.6

10

1

Pancreatic disease

 PDAC

56

0.73

0.31–1.67

0.45

 Non-PDAC

66

1

Location

 Body

70

0.67

0.29–1.55

0.35

 Tail

52

1

Operative time (min)

  > 300

41

1.43

0.60–3.33

0.42

  < 300

80

1

Blood loss (ml)

  > 400

42

0.92

0.37–2.17

0.85

  < 400

79

1

Surgical procedure

 Open

86

1.93

0.75–5.67

0.18

 Laparoscopic

36

1

 Spleen preserving

20

0.46

0.10–1.49

0.21

 Non spleen preserving

102

1

Resection procedure

 Hand-sewn

47

0.90

0.37–2.09

0.81

 Stapler

75

1

Pancreas texture

 Soft

66

6.81

2.37–24.79

 < 0.001^***

9.22

2.22–44.19

 < 0.01**

 Hard

46

1

1

Pancreas thickness (mm)

0.34–1.83

0.59

  > 12

58

0.80

  < 12

64

1

SAC (U/L) –POD1

  > 100

88

0.58

0.71–4.16

0.22

  < 100

34

1

SAC (U/L) –POD3

  > 100

16

1.01

0.27–3.20

0.98

  < 100

105

1

Drainage volume (ml)^a – POD1

  > 40

89

1.66

0.64–4.89

0.31

  < 40

33

1

Drainage volume (ml)^a – POD3

  > 55

35

0.70

0.25–1.74

0.45

  < 55

87

1

DSACR^b – POD1

  > 17

63

5.33

2.09–15.54

 < 0.001^***

1.51

0.40–5.91

0.55

  < 17

58

1

1

DSACR^b – POD3

  > 22

47

9.04

3.59–25.33

 < 0.001^***

8.76

2.78–31.59

 < 0.001***

  < 22

73

1

1