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Table 3 Univariate and Multivariate Analysis of Re-amputation

From: Impact of time in range during hospitalization on clinical outcomes in diabetic patients with toe amputation: a propensity score matching analysis

Variables

Cases without reamputation, (n = 263)

Cases with reamputation, (n = 119)

Univariate analysis P

Multivariate analysis P

Age, median (IQR), years

67.0 (58.0–74.0)

67.0 (62.0–72.0)

0.658

 

Sex, n (%)

 Male

178 (67.7%)

84 (70.6%)

0.571

 

 Female

85 (32.3%)

35 (29.4%)

BMI, median (IQR), kg/m2

23.1 (21.1–25.4)

22.7 (21.6–25.0)

0.705

 

Preoperative blood glucose, n (%)

 < 6.1

54 (20.5%)

28 (23.5%)

0.509

 

 ≥ 6.1

209 (79.5%)

91 (76.5%)

Preoperative HbA1c, n (%)

 < 7.5

61 (23.2%)

25 (21.0%)

0.636

 

 ≥ 7.5

202 (76.8%)

94 (79.0%)

Preoperative WBC, median (IQR)

8.7 (6.9–11.6)

9.0 (6.8–12.9)

0.292

 

Preoperative neutrophil, median (IQR)

6.4 (4.5–9.1)

6.4 (4.8–10.4)

0.336

 

Preoperative lymphocyte, median (IQR)

1.5 (1.1–1.8)

1.5 (1.1–1.8)

0.849

 

Preoperative platelet, median (IQR)

268.0 (209.0–353.0)

287.0 (226.5–343.5)

0.303

 

Preoperative CRP, n (%)

 < 8

63 (24.0%)

21 (17.6%)

0.168

 

 ≥ 8

200 (76.0%)

98 (82.4%)

Anemia, n (%)

 No

112 (42.6%)

44 (37.0%)

0.302

 

 Yes

151 (57.4%)

75 (63.0%)

Preoperative albumin, median (IQR)

32.9 (29.0–35.7)

31.4 (28.4–35.2)

0.188

 

Preoperative creatinine, median (IQR)

78.0 (59.0–108.0)

84.0 (61.5–112.5)

0.372

 

Smoking, n (%)

 No

205 (77.9%)

78 (65.5%)

0.010*

0.016*

 Yes

58 (22.1%)

41 (34.5%)

Drinking, n (%)

 No

202 (76.8%)

87 (73.1%)

0.436

 

 Yes

61 (23.2%)

32 (26.9%)

Hypertension, n (%)

 No

125 (47.5%)

56 (47.1%)

0.932

 

 Yes

138 (52.5%)

63 (52.9%)

Kidney disease, n (%)

 No

194 (73.8%)

81 (68.1%)

0.251

 

 Yes

69 (26.2%)

38 (31.9%)

LEAD, n (%)

 No

111 (42.2%)

17 (14.3%)

< 0.001*

< 0.001*

 Yes

152 (57.8%)

102 (85.7%)

Preoperative bacterial culture, n (%)

 Negative

114 (43.3%)

40 (33.6%)

0.073

 

 Positive

149 (56.7%)

79 (66.4%)

Wagner score, n (%)

 1–3

200 (76.0%)

84 (70.6%)

0.258

 

 4–5

63 (24.0%)

35 (29.4%)

Number of toes, n (%)

 1

187 (71.1%)

90 (75.6%)

0.359

 

 2–5

76 (28.9%)

29 (24.4%)

TIR

 < 70%

114 (43.3%)

77 (64.7%)

< 0.001*

< 0.001*

 ≥ 70%

149 (56.7%)

42 (35.3%)

  1. BMI body mass index, CRP C-reactive protein, IQR interquartile range, LEAD lower extremity arterial disease, LOS length of stay, TIR time in range
  2. *Statistical difference between the two groups