Is total thyroidectomy with bilateral central neck dissection the only surgery for papillary thyroid carcinoma patients with clinically involved central nodes?

Table 2 Associations between contralateral lobe involvement^a and clinicopathological characteristics of PTC patients (n = 643^b)

Clinicopathological characteristics	Univariate analysis			Multivariate analysis
Clinicopathological characteristics	Adjusted OR	95% CI	p-value	Adjusted OR	95% CI	p-value
Unilateral cN1a (Ref = cN0)	1.348	0.708–2.567	0.364
Male sex (Ref = female)	0.813	0.472–1.401	0.456
Patient age (per 10 years)	1.018	0.999–1.036	0.063	1.015	0.996–1.034	0.134
Tumor size (per 0.1 cm)	0.961	0.678–1.362	0.823
Multifocality (Ref = absent)	3.262	2.006–5.305	< 0.001	3.164	1.942–5.157	< 0.001
ETE (Ref = absent)	0.772	0.486–1.226	0.273
Chronic lymphocytic thyroiditis (Ref = absent)	1.320	0.813–2.141	0.261
Ipsilateral central neck metastasis (Ref = absent)	0.707	0.447–1.116	0.136

PTC papillary thyroid carcinoma, cN0 no clinically involved central lymph node, cN1a clinically involved central lymph node, ETE extrathyroidal extension, OR odds ratio, CI confidence interval, Ref reference
^aIncidentally found contralateral lobe PTMC on permanent pathology
^bPatients with preoperatively detected bilateral PTC were excluded

ISSN: 1471-2482