Table 1 Demographic and clinical data at initial hepatectomy and at recurrence time
| Â | Within Milan criteria | Beyond Milan criteria | OR | 95% CI | p value |
|---|---|---|---|---|---|
(n = 96) | (n = 75) | ||||
At initial hepatectomy | Â | Â | Â | Â | Â |
 Age (years old) | 49.6 ± 11.9 | 48.5 ± 12.5 |  |  | 0.548 |
 Gender(male/female) | 77/19 | Jul-68 |  |  | 0.085 |
 Positive HBsAg | 84 (87.5) | 67 (89.3) |  |  | 0.813 |
 HBV-DNA > 103 | 22 (29.3) | 26 (27.1) |  |  | 0.864 |
 Tumor size (cm) | 3.3 ± 1.1 | 7.9 ± 3.2 |  |  | 0.001* |
 Tumor number |  |  |  |  | 0.095 |
  One | 83 (86.5) | 55 (73.3) |  |  |  |
  Two | 10 (10.4) | 16 (21.3) |  |  |  |
  More | 3 (3.1) | 4 (5.3) |  |  |  |
 Differentiation(poor/moderate-well) | 34/62 | 27/48 |  |  | 0.52 |
 Microvascular invasion | 19 (19.8) | 29 (38.7) | 2.555 | 1.289–5.064 | 0.010* |
 Satellite lesions | 9 (9.4) | 9 (12.0) |  |  | 0.622 |
 Liver cirrhosis | 76 (79.1) | 46 (61.3) | 2.396 | 1.217–4.715 | 0.036* |
 AFP(> 400 ng/ml) | 30 (31.2) | 27 (36.0) |  |  | 0.519 |
 Recurrence time(mo) | 31.4 ± 24.2 | 20.2 ± 16.1 |  |  |  < 0.001* |
 Treatments after recurrence |  |  |  |  |  |
  Resection | 48 (50.0) | 32 (42.7) |  |  | 0.552 |
  RFA | 44 (45.8) | 38 (50.7) |  |  |  |
  Resection + RFA | 4 (4.2) | 5 (6.7) |  |  |  |
At recurrence time | Â | Â | Â | Â | Â |
 Tumor size (cm) | 3.2 ± 2.4 | 3.2 ± 2.1 |  |  | 0.845 |
 Tumor number |  |  |  |  | 0.445 |
  One | 75 (78.1) | 52 (69.3) |  |  |  |
  Two | 10 (10.4) | 11 (14.7) |  |  |  |
  More | 11 (11.5) | 12 (16) |  |  |  |
 Satellite lesions | 2 (2.1) | 1 (1.3) |  |  | 1 |
 Macrovascular invasion | 1 (1.0) | 1 (1.3) |  |  | 1 |
 Extrahepatic invasion | 3 (3.1) | 7 (9.3) |  |  | 0.107 |
  Spleen | 1(1.0) | 0 |  |  | 0.101 |
  Greater omentum | 0 | 1 (1.3) |  |  | 0.93 |
  Abdominal wall | 1 (1.0) | 1 (1.3) |  |  | 0.308 |
  Diaphragm | 1 (1.0) | 1 (1.3) |  |  | 0.198 |
  Abdominal cavity | 0 | 2 (2.7) |  |  | 0.355 |
  Colon | 0 | 1 (1.3) |  |  | 0.757 |
  Lung | 0 | 1 (1.3) |  |  | 0.266 |
 AFP(> 400 ng/ml) | 12 (12.5) | 17 (22.7) |  |  | 0.101 |
 TBIL(mmol/L) | 15.4 ± 5.9 | 15.5 ± 6.8 |  |  | 0.93 |
 ALT(U/L) | 35.2 ± 26.3 | 41.8 ± 56.3 |  |  | 0.308 |
 AST(U/L) | 33.9 ± 17.5 | 38.5 ± 27.8 |  |  | 0.198 |
 ALB(g/L) | 42.9 ± 3.7 | 42.4 ± 4.0 |  |  | 0.355 |
 PLR | 83.7 ± 52.4 | 86.2 ± 51.4 |  |  | 0.758 |
 NLR | 2.2 ± 1.1 | 2.4 ± 1.5 |  |  | 0.266 |