Table 2 Univariate analysis of postoperative morbidity and severe morbidity
Variables | Morbidity | P value | Severe morbidity | P value | |||
|---|---|---|---|---|---|---|---|
Absent, n (%) | Present, n (%) | Absent, n (%) | Present, n (%) | ||||
Sex | Man | 254 (69.8) | 110 (30.2) | 0.92 | 317 (87.1) | 47 (12.9) | 0.15 |
Woman | 155 (70.1) | 66 (29.8) | 201 (90.9) | 20 (9.1) | |||
Age | ≥ 75 | 105 (74.5) | 36 (25.5) | 0.17 | 127 (90.1) | 14 (9.9) | 0.51 |
< 75 | 304 (68.5) | 140 (31.5) | 391 (88.1) | 53 (11.9) | |||
Comorbidity | |||||||
Malignant disease | Absent | 347 (68.8) | 157 (31.2) | 0.16 | 444 (88.1) | 60 (11.9) | 0.39 |
Present | 62 (76.5) | 19 (23.5) | 74 (91.4) | 7 (8.6) | |||
Angina pectoris | Absent | 386 (70.4) | 162 (29.6) | 0.28 | 484 (88.3) | 64 (11.7) | 0.50 |
Present | 23 (62.2) | 14 (37.8) | 34 (91.9) | 3 (8.1) | |||
Cerebral infarction | Absent | 392 (69.9) | 169 (30.1) | 0.92 | 495 (88.2) | 66 (11.8) | 0.25 |
Present | 17 (70.8) | 7 (29.2) | 23 (95.8) | 1 (4.2) | |||
Interstitial lung disease | Absent | 402 (69.8) | 174 (30.2) | 0.60 | 511 (88.7) | 65 (11.3) | 0.30 |
Present | 7 (77.8) | 2 (22.2) | 7 (77.8) | 2 (22.2) | |||
Chronic renal failure | Absent | 406 (70.2) | 172 (29.8) | 0.11 | 512 (88.6) | 66 (11.4) | 0.81 |
Present | 3 (42.8) | 4 (57.2) | 6 (85.7) | 1 (14.3) | |||
Diabetes mellitus | Absent | 355 (70.4) | 149 (29.6) | 0.49 | 446 (88.5) | 58 (11.5) | 0.91 |
Present | 54 (66.7) | 27 (33.3) | 72 (88.9) | 9 (11.1) | |||
COPD | Absent | 390 (70.9) | 160 (29.1) | 0.03 | 490 (89.1) | 60 (10.9) | 0.10 |
Present | 19 (54.3) | 16 (45.7) | 28 (80.0) | 7 (20.0) | |||
Asthma | Absent | 401 (71.0) | 164 (29.0) | < 0.01 | 501 (88.7) | 64 (11.3) | 0.61 |
Present | 8 (40.0) | 12 (60.0) | 17 (85.0) | 3 (15.0) | |||
Arrhythmia | Absent | 395 (69.9) | 170 (30.1) | 0.99 | 500 (88.5) | 65 (11.5) | 0.83 |
Present | 14 (70.0) | 6 (30.0) | 18 (90.0) | 2 (10.0) | |||
Autoimmune disease | Absent | 397 (69.6) | 173 (30.3) | 0.38 | 505 (88.6) | 65 (11.4) | 0.81 |
Present | 12 (80.0) | 3 (20.0) | 13 (86.7) | 2 (13.3) | |||
Hypertension | Absent | 344 (69.8) | 149 (30.2) | 0.86 | 433 (87.8) | 60 (12.2) | 0.20 |
Present | 65 (70.6) | 27 (29.3) | 85 (92.4) | 7 (7.6) | |||
Smoking status | Brinkman index < 600 | 223 (76.9) | 67 (23.1) | < 0.01 | 263 (90.7) | 27 (9.3) | 0.10 |
Brinkman index ≥ 600 | 186 (63.1) | 109 (36.9) | 255 (86.4) | 40 (13.6) | |||
BMI | < 21.88 | 149 (67.1) | 73 (32.9) | 0.24 | 203 (91.4) | 19 (8.6) | 0.08 |
≥ 21.88 | 260 (71.6) | 103 (28.4) | 315 (86.8) | 48 (13.2) | |||
CEA | ≤ 5 | 299 (72.6) | 113 (27.4) | 0.03 | 367 (89.1) | 45 (10.9) | 0.53 |
> 5 | 110 (63.6) | 63 (36.4) | 151 (87.3) | 22 (12.7) | |||
PNI | ≥ 49.68 | 228 (73.3) | 83 (26.7) | 0.05 | 282 (90.7) | 29 (9.3) | 0.08 |
< 49.68 | 181 (66.1) | 93 (33.9) | 236 (86.1) | 38 (13.9) | |||
NLR | ≤ 1.56 | 108 (78.3) | 30 (20.0) | 0.01 | 124 (89.9) | 14 (10.1) | 0.58 |
> 1.56 | 301 (67.3) | 146 (32.7) | 394 (88.1) | 53 (11.9) | |||
%VC | ≥ 80 | 402 (70.3) | 170 (29.7) | 0.20 | 510 (89.2) | 62 (10.8) | < 0.01 |
< 80 | 7 (53.8) | 6 (46.2) | 8 (61.5) | 5 (38.5) | |||
FEV1% | ≥ 70 | 285 (75.4) | 93 (24.6) | < 0.01 | 341 (90.2) | 37 (8.6) | 0.08 |
< 70 | 124 (59.9) | 83 (40.1) | 177 (85.5) | 30 (14.5) | |||
Pulmonary lobe of NSCLC | RUL | 120 (67.0) | 59 (33.0) | 0.01 | 157 (87.7) | 22 (12.3) | 0.16 |
RML | 31 (83.8) | 6 (16.2) | 34 (91.9) | 3 (8.1) | |||
RLL | 97 (70.8) | 40 (29.2) | 122 (89.1) | 15 (10.9) | |||
LUL | 87 (62.6) | 52 (37.4) | 117 (84.2) | 22 (15.8) | |||
LLL | 74 (79.6) | 19 (20.4) | 88 (94.6) | 5 (5.4) | |||
RUL or RLL or LUL | 304 (66.8) | 151 (33.2) | < 0.01 | 396 (87.0) | 59 (13.0) | 0.03 | |
RML or LLL | 105 (80.8) | 25 (19.2) | 122 (93.9) | 8 (6.1) | |||
Histological type | Non-Squamous cell carcinoma | 343 (71.9) | 134 (28.1) | 0.02 | 432 (90.6) | 45 (9.4) | < 0.01 |
Squamous cell carcinoma | 66 (61.1) | 42 (38.9) | 86 (79.6) | 22 (20.4) | |||
Operative approach | VATS or RATS | 362 (69.6) | 158 (30.4) | 0.65 | 464 (89.2) | 56 (10.8) | 0.14 |
Open thoracotomy | 47 (72.3) | 18 (27.7) | 54 (83.1) | 12 (16.9) | |||
Operative procedure | Except for segmentectomy | 356 (68.9) | 161 (31.1) | 0.12 | 452 (87.4) | 65 (12.6) | 0.01 |
Segmentectomy | 53 (77.9) | 15 (22.1) | 66 (97.1) | 2 (2.9) | |||
Except for lobectomy | 78 (69.6) | 34 (30.4) | 0.94 | 97 (86.6) | 15 (13.4) | 0.47 | |
Lobectomy | 331 (70.0) | 142 (30.0) | 421 (89.0) | 52 (11.0) | |||
Except for extend-lobectomy | 396 (70.8) | 163 (29.2) | 0.02 | 499 (89.3) | 60 (10.7) | 0.01 | |
Extend-lobectomy | 13 (50.0) | 13 (50.0) | 19 (73.1) | 7 (26.9) | |||
Except for pneumonectomy | 397 (70.0) | 170 (30.0) | 0.76 | 506 (89.2) | 61 (10.8) | < 0.01 | |
Pneumonectomy | 12 (66.7) | 6 (33.3) | 12 (66.7) | 6 (33.3) | |||