Table 2 Risk factors of lymph node metastasis by univariate analysis
Variables | N0 | N1 + N2 | P value |
|---|---|---|---|
Gender | 0.296 | ||
Male | 196 | 25 | |
Female | 366 | 35 | |
Age | 0.715 | ||
< 60 | 248 | 25 | |
≥ 60 | 314 | 35 | |
Smoking history | 0.017 | ||
Yes | 112 | 20 | |
No | 447 | 40 | |
CEA level (ng/ml) | < 0.001 | ||
≤ 5 | 499 | 34 | |
> 5 | 53 | 26 | |
Tumor size (cm) | 1.64 ± 0.62 | 2.17 ± 0.56 | < 0.001 |
Lobe distribution | 0.748 | ||
Right upper lobe | 186 | 16 | |
Right middle lobe | 30 | 3 | |
Right lower lobe | 74 | 7 | |
Left upper Lobe | 159 | 18 | |
Left lower lobe | 113 | 16 | |
Tumor location | 0.008 | ||
Central | 14 | 6 | |
Peripheral | 548 | 54 | |
CTR | < 0.001 | ||
≤ 0.5 | 308 | 1 | |
> 0.5 | 254 | 59 | |
Pleural invasion | < 0.001 | ||
Yes | 46 | 16 | |
No | 516 | 44 | |
Pathologic type | < 0.001 | ||
MIA | 34 | 0 | |
LPA | 89 | 0 | |
IA | 439 | 60 |