Table 3 Univariate logistic regression analyses of anastomotic leakage

Age (years)

 <65

20 (40%)

8 (50%)

1.500

0.484–4.651

0.483

 ≥65

30 (60%)

8 (50%)

1

Sex

 Male

42 (84%)

15 (94%)

2.857

0.329–24.795

0.341

 Female

8 (16%)

1 (6%)

1

Body mass index (kg/m²)

 <22

24 (48%)

10 (63%)

1.806

0.569–5.726

0.316

 ≥ 22

26 (52%)

6 (38%)

1

Serum albumin level (g/dL)

 <4

20 (40%)

5 (31%)

0.682

0.206–2.261

0.531

 ≥ 4

30 (60%)

11 (69%)

1

Brinkman index

 <800

24 (48%)

3 (19%)

0.250

0.063–0.986

0.048

 ≥ 800

26 (52%)

13 (81%)

1

Performance status

 0

42 (84%)

13 (81%)

0.825

0.191–3.574

0.797

 1, 2

8 (16%)

3 (19%)

1

Diabetes

 Absent

39 (78%)

13 (81%)

1.222

0.295–5.069

0.782

 Present

11 (22%)

3 (19%)

1

Cardiovascular disease

 Absent

46 (92%)

13 (81%)

0.377

0.075–1.901

0.237

 Present

4 (8%)

3 (19%)

Obstructive ventilation failure

 Absent

36 (72%)

9 (56%)

0.500

0.156–1.603

0.243

 Present

14 (28%)

7 (44%)

1

ASA-PS score

 1

3 (6%)

1 (6%)

1.044

0.101–10.806

0.971

 2, 3

47 (94%)

15 (94%)

1

Histological type

 Squamous cell carcinoma

45 (90%)

15 (94%)

1.667

0.180–15.425

0.653

 Others

5 (10%)

1 (6%)

1

Tumor location

 Ut, Mt

31 (62%)

11 (69%)

1.348

0.406–4.484

0.626

 Lt, Ae

19 (38%)

5 (31%)

1

cT

 1

21 (42%)

9 (56%)

1.776

0.570–5.531

0.322

 2, 3, 4a

29 (58%)

7 (44%)

1

cN

 Absent

33 (66%)

10 (63%)

0.859

0.267–2.764

0.798

 Present

17 (34%)

6 (38%)

1

cStage

 1

20 (40%)

9 (56%)

1.929

0.618–6.020

0.258

 2, 3

30 (60%)

7 (44%)

1

Neoadjuvant chemotherapy

 Absent

22 (44%)

10 (63%)

2.121

0.668–6.739

0.202

 Present

28 (56%)

6 (38%)

1

Abdominal approach

 Open

11 (22%)

4 (25%)

1.182

0.317–4.400

0.803

 Laparoscopic

39 (78%)

12 (75%)

1

Lymph node dissection

 Two-field

15 (30%)

5 (31%)

1.061

0.314–3.585

0.925

 Three-field

35 (70%)

11 (69%)

1

Route of reconstruction

 Retrosternal

43 (86%)

15 (94%)

2.442

0.277–21.519

0.421

 Posterior mediastinal

7 (14%)

1 (6%)

1

Shape of gastric tube

 Wide

5 (10%)

3 (19%)

2.077

0.437–9.871

0.358

 Narrow

45 (90%)

13 (81%)

1

Total operative time (min)

 <600

20 (40%)

6 (38%)

0.900

0.282–2.870

0.859

 ≥ 600

30 (60%)

10 (63%)

1

Blood loss (mL)

 <100

26 (52%)

7 (44%)

0.718

0.231–2.229

0.566

 ≥ 100

24 (48%)

9 (56%)

1

Anastomotic method

 ICG circular group

30 (60%)

3 (19%)

0.154

0.039–0.610

0.008

 Classical group

20 (40%)

13 (81%)

1