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Table 4 Factors associated with surgical site infection among patients who underwent major abdominal surgery at MNRH during the study period

From: Elevated serum lactate as a predictor of outcomes in patients following major abdominal surgery at a tertiary hospital in Uganda

Characteristic Univariate Multivariate
cOR 95% CI p-value aOR 95% CI p-value
Age       
  < 18 years 1      
  ≥ 18 years 2.70 1.94–3.75  < 0.001 1.41 0.58–3.45 0.455
Type of surgery       
 Elective 1      
 Emergency 2.51 1.88–3.36  < 0.001 1.33 0.55–3.21 0.521
ASA status       
 I 1      
 II 0.78 0.44–1.26 0.675 0.79 0.74–2.14 0.389
 III 1.42 0.95–4.55 0.080 1.10 0.23–1.98 0.078
 IV 3.64 1.59–7.65 0.042 2.60 0.81–3.78 0.090
Duration between diagnosis and surgery (days)       
 Within 1 day 1      
 Longer than a day 3.23 2.05–5.07  < 0.001 1.69 0.57–4.99 0.345
Duration of surgery (hours)       
  ≤ 1.5 1      
  > 1.5 2.98 1.93–4.60  < 0.001 1.63 0.63–4.35 0.307
Pre-surgery treatment       
 Yes 1      
 No 4.65 2.91–7.44  < 0.001 6.20 1.12–4.26 0.036
Intra operative care (litres)       
  ≤ 1 1      
  > 1 0.37 0.25–0.58  < 0.001 0.81 0.18–3.58 0.780
Comorbidities       
 No 1      
 Yes 1.13 1.09–1.17  < 0.001 1.01 0.84 -1.22 0.894
Organs involved       
 One organ 1      
 More than one organ 3.35 1.16–5.46  < 0.001 1.02 0.81–1.28 0.873
Serum lactate       
 Normal (≤ 2.0 mmol/L) 1      
 High (> 2.0 mmol/L) 2.87 1.99–4.13  < 0.001 1.25 1.11–3.70 0.008
  1. The bold was indicative of the statistically significant p values of different variables
  2. SSI n = 36; 14.6%