Characteristic | HIFU (N = 8) | BSC (N = 16) | PC (N = 16) | p value |
---|---|---|---|---|
Previous lines of liver metastases therapy | NA | |||
 Nil | 4 | 16 | 16 |  |
 1 | 3 | 0 | 0 |  |
 2 | 1 | 0 | 0 |  |
Time from initial diagnosis to HIFU (month), (range) | 0–7 | – | – |  |
Time between last liver-directed therapy and HIFU (month), (range) | 0–5 | – | – |  |
Number |  > 0.1 | |||
 1 | 5 | 8 | 8 |  |
 2 | 1 | 4 | 3 |  |
 3 | 2 | 4 | 5 |  |
Maximum size (cm), Median (range) | 2.0 (1.2–8.8) | 3.8 (1.0–8.0) | 3.0 (1.0–7.0) |  > 0.1 |
Location (liver segment) | NA | |||
 I | 0 | 2 | 1 |  |
 II | 1 | 1 | 3 |  |
 III | 1 | 1 | 2 |  |
 IV | 1 | 5 | 1 |  |
 V | 1 | 3 | 4 |  |
 VI | 4 | 7 | 6 |  |
 VII | 1 | 1 | 3 |  |
 VIII | 2 | 2 | 4 |  |
Systematic treatment after HIFU | Â | |||
 No | 1 | – | – |  |
 Yes | 7 | – | – |  |
Input energy of HIFU (kJ), Median(IQR) | 625 (353–848) | – | – |  |
Input power of HIFU (W), Median(IQR) | 340 (297–360) | – | – |  |
Cumulative transmit time of HIFU (s), Median(IQR) | 1890 (1230–2219) | – | – |  |