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Table 3 Risk factors for severe complications

From: Morbidity and mortality after liver surgery for colorectal liver metastases: a cohort study in a high-volume fast-track programme

 

Univariate

 

Multivariate

 
 

OR for ≥ Grade 3a (95% CI)

p-value

OR for ≥ Grade 3a (95% CI)

p-value

Age at surgery per 10 year

1.1 (0.9–1.4)

0.161

  

Male

2.5 (1.5–4.2)

0.001

2.3 (1.4–4.0)

0.002

ASA

    

 1

Ref

Ref

  

 2

1.1 (0.5–2.6)

0.808

  

 3 or more

1.5 (0.6–3.7)

0.394

  

Liver surgery number

    

 One, n (%)

Ref

Ref

  

 Two, n (%)

1.1 (0.6–1.9)

0.790

  

 Three or more, n (%)

2.0 (0.9–4.3)

0.066

  

Surgery duration per 30 min

1.2 (1.1–1.4)

 < 0.001

1.1 (1.0–1.3)

0.013

Laparoscopic

NA

NA

  

Number of local resections

    

 One

Ref

   

 Two

0.4 (0.1–1.1)

0.079

  

 Three

0.4 (0.1–1.9)

0.260

  

 Four or more

1.3 (0.5–3.4)

0.541

  

Type of surgery

    

 Local resection only

Ref

Ref

  

 4 or more segments

3.4 (1.9–6.0)

 < 0.001

  

 3 segments

3.8 (1.7–8.7)

0.001

  

 2 segments

1.1 (0.5–2.7)

0.800

  

 1 segment

1.3 (0.6–3.1)

0.540

  

 RFA only

2.2 (0.9–5.1)

0.080

  

Local resection 4 or more

1.8 (0.7–4.5)

0.190

  

Major resection (≥ 3 segments)

2.9 (1.8–4.6)

 < 0.001

2.2 (1.3–3.7)

0.003

Extrahepatic resection

0.6 (0.2–1.6)

0.286

  

Preoperative bilirubin, logarithmic transformed

1.4 (0.9–2.4)

0.2

  

Preoperative ALAT, logarithmic transformed

1.1 (0.7–1.7)

0.8

  
  1. To analyse risk factors for severe complications (≥ Grade 3a) univariate and multivariate logistic regression models were done. Major resection (≥ 3 segments) were comprised from the results of the univariate model, thus were other types of surgery not included in the multivariate model. NA (non-applicable) is used as there were no severe complications. OR odds ratio, N number, RFA radio-frequency ablation, ASA American Society of Anaesthesiologists score, ALAT alanine transaminase