From: Analysis of risk factors and prognosis of 253 lymph node metastasis in colorectal cancer patients
253 lymph node negative group (n = 381) | 253 lymph node positive group (n = 10) | P | |
---|---|---|---|
Tumor location | 0.087 | ||
Rectum | 254 (66.6%) | 3 (30.0%) | |
Sigmoid colon | 94 (24.7%) | 6 (60.0%) | |
Rectum sigmoid colon junction | 9 (2.4%) | 1 (10.0%) | |
Others | 24 (6.3%) | 0 (0.0%) | |
Tumor max diameter: cm | 3.8 ± 1.8 | 5.0 ± 2.0 | 0.034 |
Differentiation | 0.011 | ||
Well | 3 (0.9%) | 0 (0.0%) | |
Moderately | 284 (83.8%) | 4 (44.4%) | |
Poorly | 52 (15.3%) | 5 (55.6%) | |
Histopathological type | 0.016 | ||
Adenocarcinoma | 329 (91.9%) | 8 (80.0%) | |
Mucinous adenocarcinoma | 11 (3.1%) | 0 (0.0%) | |
Signet-ring cell carcinoma | 3 (0.8%) | 1 (10.0%) | |
Others | 15(4.2%) | 1 (10.0%) | |
T stage | 0.118 | ||
Tis | 2 (0.6%) | 0 (0.0%) | |
T1 | 21 (5.8%) | 0 (0.0%) | |
T2 | 57 (15.8%) | 1 (10.0%) | |
T3 | 230 (63.7%) | 6 (60.0%) | |
T4a | 48 (13.3%) | 2 (20.0%) | |
T4b | 3 (0.8%) | 1 (10.0%) | |
N stage | < 0.001 | ||
N0 | 230 (61.5%) | 0 (0.0%) | |
N1a | 47 (12.6%) | 2 (20.0%) | |
N1b | 43 (11.5%) | 1 (10.0%) | |
N2a | 29 (7.8%) | 3 (30.0%) | |
N2b | 25 (6.7%) | 4 (40.0%) | |
M Stage | < 0.001 | ||
M0 | 367 (98.1%) | 7 (77.8%) | |
M1 | 6 (1.6%) | 1 (11.1%) | |
M1b | 1 (0.3%) | 0 (0.0%) | |
M1c | 0 (0.0%) | 1 (11.1%) | |
TNM stage | 0.049 | ||
I | 23 (6.4%) | 0 (0.0%) | |
II | 130 (36.1%) | 0 (0.0%) | |
III | 143 (39.7%) | 6 (60.0%) | |
IV | 64 (17.8%) | 4 (40.0%) | |
Nerve invasion | 0.209 | ||
No | 342 (91.4%) | 8 (80.0%) | |
Yes | 32 (8.6%) | 2 (20.0%) | |
Vessel carcinoma embolus | 0.001 | ||
No | 338 (90.9%) | 6 (60.0%) | |
Yes | 34 (9.1%) | 4 (40.0%) | |
Cancerous node | 0.134 | ||
No | 323 (86.6%) | 7 (70.0%) | |
Yes | 50 (13.4%) | 3 (30.0%) | |
Number of harvested lymph nodes | 14.4 ± 4.9 | 18.0 ± 7.1 | 0.027 |
Number of metastatic lymph nodes | 0.0 (0.0–2.0) | 4.0 (2.5–7.8) | < 0.001 |
Number of 253 lymph nodes | 1.0 (0.0–3.0) | 2.0 (1.2-4.0) | 0.036 |