Table 4 Prognostic factors for DFS for ICC patients in Univariate analysis

Age ≥ 60 years

0.797 (0.541–1.174)

Preoperative CEA > 5 ng/mL

2.210 (1.442–3.386)

Male

1.119 (0.764–1.640)

RDW-SD > 40.2 fl

0.681 (0.459–1.011)

BMI ≥ 24 kg/m²

1.014 (0.689–1.492)

RDW-CV > 12.6%

0.896 (0.608–1.320)

ASA score 3–4

1.352 (0.703–2.599)

ALB ≥ 40 g/L

0.744 (0.478–1.159)

Cirrhosis

1.101 (0.743–1.632)

TBIL > 21 umol/L

0.912 (0.488–1.703)

HBsAg ( +)

1.193 (0.765–1.858)

AST > 40 U/L

1.606 (0.898–2.873)

T3-T4 stage

1.711 (1.100–2.662)

ALT > 50U/L

2.018 (1.120–3.634)

Lymphnode metastasis

Operation time ≥ 230 min^a

1.380 (0.941–2.022)

Undissected lymph node

Reference

Blood loss ≥ 300 ml^a

1.710 (1.149–2.546)

Negative lymph node

1.114 (0.685–1.811)

Major liver resection

1.402 (0.906–2.171)

Positive lymph node

2.713 (1.591–4.627)

Post-operative Complications

0.998 (0.674–1.477)

Tumor size ≥ 5 cm

1.285 (0.877–1.884)

Preoperative therapy

1.207 (0.587–2.484)

Multiple tumors

1.738 (1.099–2.751)

Adjuvant therapy

0.887 (0.602–1.306)

Tumor location (central tumor)

0.702 (0.480–1.028)

The prognostic value on SCC score

Tumor location (right lobe)

0.906 (0.672–1.222)

SCC = 0

Reference

Poor differentiation

1.443 (0.965–2.158)

SCC = 1

0.716 (0.447–1.146)

Preoperative CA19-9 > 27 U/mL

1.364 (0.875–2.124)

SCC = 2

0.698 (0.438–1.113)