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Table 3 Univariate analysis of factors influencing 5-year survival after resection of oligometastatic EGAC

From: Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival

  n 5-year-survival (%) Median survival in years p = 
Total 48 18 1.3  
Sex
 Female 15 26 2.8 0.195
 Male 33 16 1  
Age
 < 65 35 10 1.2 0.596
 ≥ 65 13 26 1.4  
ASA classification
 ASA 1–2 29 20 1.3 0.405
 ASA 3–4 19 16 1  
Type of carcinoma
 Esophageal carcinoma 17 10% 1 0.213
 Gastric carcinoma 31 24% 1.3  
Preoperative T stage
 T2 1 0 0.5 0.338
 T3 29 14% 1.2  
 T4 5 0 3.9  
Type of surgery
 Esophagectomy 16 0 1 0.099
 Gastrectomy 32 30 1.3  
Resection margin
 R0 33 21 1.4 0.273
 R1 (primary tumor) 4 0 0.4  
 R2 (non-resected metastases) 11 17 1.3  
Tumor regression grading
 1a 6 60 Not reached 0.012
 1b-2 22 11 1.8  
 03-Apr 20 12 0.9  
Postop. pathologic T stage
 T0 6 60 Not reached 0.047
 T1–T2 15 27 1.3  
 T3–T4 27 0 1  
Postop. pathologic N stage
 N0 17 31 2.9 0.062
 N+  31 11 1.2  
Type of metastasis
 Peritoneal carcinomatosis 30 11 1 0.945
 Lymph nodes 7 43 1.3  
 Hepatic 7 40 2.9  
 Adrenal 3 0 0.9  
 Pulmonary 1 0 1.7  
 ypM0 12 48 3.9 0.427
 ypM1 and complete resection of metastasis 25 9 1  
 ypM1 and no complete resection of metastasis 11 17 1.3  
Status of metastasis
 No 12 48 3.9 0.012
 Yes 36 11 1  
Adjuvant chemotherapy
 Yes 31 21 1.7 0.182
 No 9 30 0.5