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Table 3 Univariate analysis of factors influencing 5-year survival after resection of oligometastatic EGAC

From: Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival

 

n

5-year-survival (%)

Median survival in years

p = 

Total

48

18

1.3

 

Sex

 Female

15

26

2.8

0.195

 Male

33

16

1

 

Age

 < 65

35

10

1.2

0.596

 ≥ 65

13

26

1.4

 

ASA classification

 ASA 1–2

29

20

1.3

0.405

 ASA 3–4

19

16

1

 

Type of carcinoma

 Esophageal carcinoma

17

10%

1

0.213

 Gastric carcinoma

31

24%

1.3

 

Preoperative T stage

 T2

1

0

0.5

0.338

 T3

29

14%

1.2

 

 T4

5

0

3.9

 

Type of surgery

 Esophagectomy

16

0

1

0.099

 Gastrectomy

32

30

1.3

 

Resection margin

 R0

33

21

1.4

0.273

 R1 (primary tumor)

4

0

0.4

 

 R2 (non-resected metastases)

11

17

1.3

 

Tumor regression grading

 1a

6

60

Not reached

0.012

 1b-2

22

11

1.8

 

 03-Apr

20

12

0.9

 

Postop. pathologic T stage

 T0

6

60

Not reached

0.047

 T1–T2

15

27

1.3

 

 T3–T4

27

0

1

 

Postop. pathologic N stage

 N0

17

31

2.9

0.062

 N+ 

31

11

1.2

 

Type of metastasis

 Peritoneal carcinomatosis

30

11

1

0.945

 Lymph nodes

7

43

1.3

 

 Hepatic

7

40

2.9

 

 Adrenal

3

0

0.9

 

 Pulmonary

1

0

1.7

 

 ypM0

12

48

3.9

0.427

 ypM1 and complete resection of metastasis

25

9

1

 

 ypM1 and no complete resection of metastasis

11

17

1.3

 

Status of metastasis

 No

12

48

3.9

0.012

 Yes

36

11

1

 

Adjuvant chemotherapy

 Yes

31

21

1.7

0.182

 No

9

30

0.5