Variables | 0 | 1 month | 3 months | 6 months | 12 months | 24 months | p-value | |
---|---|---|---|---|---|---|---|---|
FPG (mg/dl) | < 45 | 109 (100–132) | 98 (90–108) | 95 (87–102) | 97 (89–106) | 92 (84–98) | 92 (87–98) | < 0.001 |
FPG (mg/dl) | ≥ 45 | 103.5 (94.5–113) | 105 (95–115) | 99.5 (91–108) | 100 (92–109) | 95 (90–100) | 97 (88–103) | < 0.001 |
p-value ≥ 45 vs. < 45 | < 0.001 | < 0.001 | < 0.001 | 0.026 | 0.001 | 0.005 | ||
Insulin (mIU/l) | < 45 | 20.6 (13.6–29.3) | 11.5 (7.9–16.7) | 10.15 (7.2–14.5) | 9.2 (5.1–15.7) | 7.9 (6–12.5) | 11.9 (7.9–18.7) | < 0.001 |
Insulin (mIU/l) | ≥ 45 | 24.3 (16.5–34.5) | 11.8 (8.1–16.1) | 10.85 (7.8–15.6) | 8.3 (5.5–13.7) | 8.6 (6.8–11.8) | 13.3 (8.2–16.75) | < 0.001 |
p-value ≥ 45 vs. < 45 | 0.003 | 0.227 | 0.281 | 0.978 | 0.240 | 0.784 | ||
HOMA-IR | < 45 | 5.41 (3.26–8.78) | 2.69 (1.63–3.71) | 2.22 (1.42–3.26) | 1.84 (0.97–3.66) | 1.50 (1.14–2.64) | 2.59 (1.60–3.77) | < 0.001 |
HOMA-IR | ≥ 45 | 6.8 (4.19–10.29) | 2.86 (1.86–4.09) | 2.53 (1.63–3.39) | 1.75 (1.17–3.03) | 1.77 (1.36–2.49) | 2.81 (1.71–3.76) | < 0.001 |
p-value ≥ 45 vs. < 45 | < 0.001 | 0.060 | 0.060 | 0.748 | 0.104 | 0.886 | ||
HbA1c (%) | < 45 | 5.5 (5.2–5.9) | 5.3 (5–5.8) | 5.2 (5–5.6) | 5.2 (4.7–5.4) | 5.1 (5–5.4) | 5.4 (5.1–5.6) | < 0.001 |
HbA1c (%) | ≥ 45 | 5.8 (5.4–6.6) | 5.7 (5.3–6.2) | 5.4 (5.2–5.9) | 5.4 (4.9–5.7) | 5.3 (5.1–5.6) | 5.5 (5.1–5.8) | < 0.001 |
p-value ≥ 45 vs. < 45 | < 0.001 | < 0.001 | < 0.001 | 0.001 | 0.001 | 0.064 |