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Table 3 Risk factors for liver metastasis identified by univariate logistic regression analysis and multivariate logistic regression analysis

From: A novel nomogram for predicting liver metastasis in patients with gastrointestinal stromal tumor: a SEER-based study

Characteristics Univariate logistic regression analysis Multivariate logistic regression analysis
OR 95% CI P OR 95% CI P
Age    0.336    
  ≤ 65 1      
  > 65 0.890 0.701–1.129 0.336    
Sex     < 0.001    0.015
 Male 1    1   
 Female 0.631 0.498–0.800   0.723 0.557–0.939 0.015
Race    0.146    
 White 1      
 Black 1.194 0.892–1.599 0.233    
 Others 0.786 0.547–1.129 0.192    
Marriage    0.254    
 Married 1      
 Unmarried 1.223 0.962–1.556 0.101    
 Unknown 1.156 0.680–1.965 0.593    
Tumor location     < 0.001    0.057
 Stomach 1    1   
 Duodenum 1.418 0.831–2.421 0.200 0.994 0.554–1.784 0.985
 Jejunum 1.305 0.799–2.130 0.287 1.403 0.826–2.381 0.210
 Ileum 0.399 0.124–1.286 0.124 0.377 0.110–1.293 0.121
 Colon 1.947 0.929–4.079 0.078 0.686 0.312–1.511 0.350
 Rectum 0.588 0.210–1.645 0.312 0.226 0.079–0.647 0.006
 Others 3.069 2.198–4.285  < 0.001 1.043 0.708–1.537 0.831
 Unknown 1.524 1.129–2.058 0.006 1.049 0.752–1.463 0.778
Tumor size     < 0.001     < 0.001
  ≤ 2 cm 1    1   
 2–5 cm 1.045 0.593–1.841 0.880 1.123 0.623–2.024 0.700
 5–10 cm 1.790 1.052–3.045 0.032 1.584 0.910–2.755 0.104
  > 10 cm 3.903 2.329–6.541  < 0.001 2.842 1.649–4.897  < 0.001
 Unknown 10.493 6.048–18.026  < 0.001 4.251 2.359–7.660  < 0.001
N stage     < 0.001     < 0.001
 N0 1    1   
 N1 6.046 3.932–9.296  < 0.001 3.313 2.057–5.337  < 0.001
 Unknown 6.365 4.123–9.824  < 0.001 2.851 1.723–4.716  < 0.001
Mitotic rate     < 0.001     < 0.001
  < 5/50 HPFs 1    1   
  ≥ 5/50 HPFs 2.219 1.507–3.266  < 0.001 1.803 1.210–2.687 0.004
 Unknown 7.615 5.599–10.365  < 0.001 5.763 4.091–8.116  < 0.001
  1. OR odds ratio, 95% CI 95% confidence interval, HPFs high power fields