Table 9 Tumor characteristics and surgical outcomes in Low and High PNI groups according to liver fictional preserve
LHL15 ≥ 0.9 | LHL15 < 0.9 | |||||
|---|---|---|---|---|---|---|
Variables | Low PNI (n = 7) | High PNI (n = 146) | p value | Low PNI (n = 10) | High PNI (n = 26) | p value |
Tumor size (cm) | 7.0 (2.0–13.0) | 4.0 (0.5–24.0) | n.s | 3 (1.1–15.0) | 3.5 (0.7–20.0) | n.s |
Multiple tumor | 2 (29%) | 38 (26%) | n.s | 5 (50%) | 4 (15%) | n.s |
AFP (ng/ml) | 40 (2–33,430) | 9 (1–253,875) | n.s | 122 (9–60,105) | 29 (4–88,940) | n.s |
DCP (mAU/ml) | 1501 (28–85,330) | 88 (1–286,400) | n.s | 260 (14–29,182) | 237 (10–174,400) | n.s |
BCLC stage | n.s | n.s | ||||
0 | 0 (0%) | 13 (9%) | 0 (0%) | 4 (15%) | ||
A | 6 (86%) | 91 (62%) | 7 (70%) | 17 (65%) | ||
B | 0 (0%) | 31 (21%) | 3 (30%) | 4 (15%) | ||
C | 1 (14%) | 11 (8%) | 0 (0%) | 1 (4%) | ||
Within Milan criteria | 9 (53%) | 98 (57%) | n.s | 7 (70%) | 20 (77%) | n.s |
Tumor differentiation | n.s | |||||
Well | 2 (29%) | 34 (29%) | 0 (0%) | 6 (29%) | n.s | |
Moderately | 3 (43%) | 68 (56%) | 7 (78%) | 12 (57%) | ||
Poorly | 2 (29%) | 19 (16%) | 2 (22%) | 3 (14%) | ||
Vascular invasion | ||||||
vp ( +) | 4 (57%) | 48 (38%) | n.s | 5 (56%) | 7 (33%) | n.s |
vv ( +) | 1 (14%) | 11 (9%) | n.s | 0 (0%) | 0 (0%) | n.s |
Operation time (minutes) | 361 (170–526) | 350 (137–983) | n.s | 277 (159–413) | 274 (127–580) | n.s |
Blood loss (ml) | 2865 (520–10,382) | 1064 (0–36,000) | n.s | 1711 (1270–4192) | 1500 (56–7341) | n.s |
≥ 2 sectionectomy | 3 (43%) | 52 (36%) | n.s | 0 (0%) | 2 (8%) | n.s |
Complications (C–D ≥ IIIa) | 1 (14%) | 29 (20%) | n.s | 4 (40%) | 4 (15%) | n.s |
Mortality | 1 (14%) | 8 (6%) | n.s | 1 (10%) | 0 (0%) | n.s |
PT-INR on POD5 | 1.19 (1.10–1.71) | 1.12 (0.92–1.52) | n.s | 1.21 (0.98–1.49) | 1.18 (0.94–1.51) | n.s |
Total bilirubin on POD5 (mg/dl) | 1.5 (0.7–11.2) | 0.9 (0.3–8.3) | 0.024 | 1.2 (0.5–2.8) | 1.0 (0.4–4.7) | n.s |